Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q4AV
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| Former ID |
DNC009662
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| Drug Name |
N-(quinolin-6-yl)-6-(sulfamoylamino)hexanamide
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| Synonyms |
CHEMBL454438; N-(quinolin-6-yl)-6-(sulfamoylamino)hexanamide; SCHEMBL5359458; CGIYOYXFUHZSMD-UHFFFAOYSA-N
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H20N4O3S
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| Canonical SMILES |
C1=CC2=C(C=CC(=C2)NC(=O)CCCCCNS(=O)(=O)N)N=C1
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| InChI |
1S/C15H20N4O3S/c16-23(21,22)18-10-3-1-2-6-15(20)19-13-7-8-14-12(11-13)5-4-9-17-14/h4-5,7-9,11,18H,1-3,6,10H2,(H,19,20)(H2,16,21,22)
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| InChIKey |
CGIYOYXFUHZSMD-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histone deacetylase 6 (HDAC6) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Alcoholism | |||
| Viral carcinogenesis | ||||
| Pathway Interaction Database | Signaling events mediated by HDAC Class II | |||
| Signaling events mediated by HDAC Class I | ||||
| Reactome | NOTCH1 Intracellular Domain Regulates Transcription | |||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | ||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | ||||
| Assembly of the primary cilium | ||||
| WikiPathways | Ectoderm Differentiation | |||
| Neural Crest Differentiation | ||||
| Cell Cycle | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Sulfamides as novel histone deacetylase inhibitors. Bioorg Med Chem Lett. 2009 Jan 15;19(2):336-40. | |||
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