Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Q4TK
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| Former ID |
DAP001405
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| Drug Name |
Morantel tartrate
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| Synonyms |
Paratect; Banminth II; MORANTEL TARTRATE SALT; Morantel tartrate [USAN]; Morantel tartrate hydrate; CP 12009-18; Morantel tartrate (USP); Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)vinyl)-, (E)-, tartrate (1:1); Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)vinyl)-, (E)-,tartrate (1:1); Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)ethenyl)-, (E)-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1); Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)ethenyl)-, (E)-,(R-(R*,R*))-2,3-dihydroxybutanedioate (1:1); (E)-1,4,5,6-Tetrahydro-1-methyl-2-(2-(3-methyl-2-thienyl)vinyl)pyrimidine tartrate (1:1); 1-methyl-2-[(E)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4H-pyrimidine; 2,3-dihydroxybutanedioic acid
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| Drug Type |
Small molecular drug
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| Indication | Mature gastrointestinal nematode infection [ICD-11: 1F6Y; ICD-10: B77-B81; ICD-9: 127] | Approved | [1] | |
| Therapeutic Class |
Anthelmintics
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| Structure |
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Download2D MOL |
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| Formula |
C16H22N2O6S
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| Canonical SMILES |
CC1=C(SC=C1)C=CC2=NCCCN2C.C(C(C(=O)O)O)(C(=O)O)O
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| InChI |
1S/C12H16N2S.C4H6O6/c1-10-6-9-15-11(10)4-5-12-13-7-3-8-14(12)2;5-1(3(7)8)2(6)4(9)10/h4-6,9H,3,7-8H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)/b5-4+;/t;1-,2-/m.1/s1
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| InChIKey |
GGXQONWGCAQGNA-UUSVNAAPSA-N
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| CAS Number |
CAS 26155-31-7
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Fumarate reductase flavoprotein (Bact frdA) | Target Info | Inhibitor | [2], [3] |
| References | Top | |||
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| REF 1 | Morantel tartrate. Canadian Food Inspection Agency. Government of Canada. 2010-08. | |||
| REF 2 | Fumarate reductase is essential for Helicobacter pylori colonization of the mouse stomach. Microb Pathog. 2000 Nov;29(5):279-87. | |||
| REF 3 | Fumarate reductase: a target for therapeutic intervention against Helicobacter pylori. Arch Biochem Biophys. 1995 Aug 1;321(1):153-9. | |||
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