Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q8EX
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| Former ID |
DNC002490
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| Drug Name |
N-Isopropyl-N'-Hydroxyguanidine
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| Synonyms |
N-ISOPROPYL-N'-HYDROXYGUANIDINE; N-HYDROXY-N'-ISOPROPYLGUANIDIE; 478806-77-8; IHG; AC1L9KDY; SCHEMBL564061; CHEMBL72434; 1-hydroxy-3-isopropylguanidine; SCHEMBL15424726; 1-hydroxy-2-propan-2-ylguanidine; (E)-2-hydroxy-1-isopropylguanidine; ZINC13535998; 2-hydroxy-1-(propan-2-yl)guanidine; AKOS017475215; AKOS011771464; 1-hydroxy-3-(1-methylethyl)guanidine; DB02143; ACM478806778
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C4H11N3O
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| Canonical SMILES |
CC(C)N=C(N)NO
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| InChI |
1S/C4H11N3O/c1-3(2)6-4(5)7-8/h3,8H,1-2H3,(H3,5,6,7)
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| InChIKey |
OITVEDMMUMUWTL-UHFFFAOYSA-N
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| CAS Number |
CAS 478806-77-8
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nitric-oxide synthase brain (NOS1) | Target Info | Inhibitor | [1] |
| BioCyc | Citrulline-nitric oxide cycle | |||
| KEGG Pathway | Arginine and proline metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Phagosome | ||||
| Circadian entrainment | ||||
| Long-term depression | ||||
| Salivary secretion | ||||
| Alzheimer's disease | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Panther Pathway | CCKR signaling map ST | |||
| Pathwhiz Pathway | Arginine and Proline Metabolism | |||
| Reactome | ROS production in response to bacteria | |||
| Nitric oxide stimulates guanylate cyclase | ||||
| WikiPathways | Monoamine Transport | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
| Spinal Cord Injury | ||||
| Alzheimers Disease | ||||
| Effects of Nitric Oxide | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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