Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0R2HZ
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| Former ID |
DIB004557
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| Drug Name |
ETHOXY-IDAZOXAN
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| Synonyms |
RX-811059; 2-(2-Ethoxy-1,4-benzodioxan-2-yl)-1-imidazoline
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| Drug Type |
Small molecular drug
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| Indication | Poison intoxication [ICD-11: NE6Z; ICD-10: T88.7] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C13H16N2O3
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| Canonical SMILES |
CCOC1(COC2=CC=CC=C2O1)C3=NCCN3
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| InChI |
1S/C13H16N2O3/c1-2-17-13(12-14-7-8-15-12)9-16-10-5-3-4-6-11(10)18-13/h3-6H,2,7-9H2,1H3,(H,14,15)
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| InChIKey |
PXTLRBYNGGDZBN-UHFFFAOYSA-N
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| CAS Number |
CAS 96576-24-8
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor alpha-2C (ADRA2C) | Target Info | Modulator | [1] |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Panther Pathway | Alpha adrenergic receptor signaling pathway | |||
| Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Reactome | Adrenoceptors | |||
| Adrenaline signalling through Alpha-2 adrenergic receptor | ||||
| Adrenaline,noradrenaline inhibits insulin secretion | ||||
| G alpha (i) signalling events | ||||
| G alpha (z) signalling events | ||||
| Surfactant metabolism | ||||
| WikiPathways | Monoamine GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Platelet Aggregation (Plug Formation) | ||||
| Integration of energy metabolism | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discriminative stimulus properties of ethoxy idazoxan. J Psychopharmacol. 1995 Jan;9(3):228-33. | |||
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