Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0R4DP
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| Former ID |
DAP000932
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| Drug Name |
Clotiazepam
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| Synonyms |
Clotiazepamum; Clozan; Distensan; Rise; Rize; Rizen; Tienor; Trecalmo; Veratran; Y 6047; Clotiazepam [INN:JAN]; Clotiazepamum [INN-Latin]; Clozan (TN); Distensan (TN); Rize (TN); Rizen (TN); Trecalmo (TN); Veratran (TN); Y-6047; Clotiazepam (JP15/INN); 2H-Thieno(2,3e)(1,4)-diazepin-2-one, 5-(o-chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-(8CI); 5-(2-Chlorophenyl)-7-ethyl-1-methyl-1,3-dihydro-2H-thieno(2,3-e)(1,4)diazepin-2-one; 5-(2-chlorophenyl)-7-ethyl-1-methyl-1,3-dihydro-2H-thieno[2,3-e][1,4]diazepin-2-one; 5-(2-chlorophenyl)-7-ethyl-1-methyl-3H-thieno[2,3-e][1,4]diazepin-2-one; 5-(o-Chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-2H-thieno(2,3-e)-1,4-diazepin-2-one
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| Drug Type |
Small molecular drug
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| Indication | Anxiety disorder [ICD-11: 6B00-6B0Z; ICD-10: R45.0] | Approved | [1] | |
| Therapeutic Class |
Hypnotics and Sedatives
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| Structure |
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Download2D MOL |
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| Formula |
C16H15ClN2OS
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| Canonical SMILES |
CCC1=CC2=C(S1)N(C(=O)CN=C2C3=CC=CC=C3Cl)C
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| InChI |
1S/C16H15ClN2OS/c1-3-10-8-12-15(11-6-4-5-7-13(11)17)18-9-14(20)19(2)16(12)21-10/h4-8H,3,9H2,1-2H3
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| InChIKey |
CHBRHODLKOZEPZ-UHFFFAOYSA-N
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| CAS Number |
CAS 33671-46-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
4821018, 7848391, 8151818, 10519139, 12015458, 15445216, 29221966, 46508776, 48415812, 50053288, 50458572, 57321476, 58106918, 104301682, 109612938, 124973749, 125823447, 126666095, 127624260, 134221992, 134338208, 135000200, 137005586, 160964803, 164838520, 179150338, 198987699, 198993221, 223668114, 224743438, 226428801, 241062689, 250113220, 252399059
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| ChEBI ID |
CHEBI:31425
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| SuperDrug ATC ID |
N05BA21
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Translocator protein (TSPO) | Target Info | Agonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| HTLV-I infection | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drug information of Clotiazepam, 2008. eduDrugs. | |||
| REF 2 | Effects of benzodiazepines and non-benzodiazepine compounds on the GABA-induced response in frog isolated sensory neurones. Br J Pharmacol. 1989 Nov;98(3):735-40. | |||
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