Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0R8VT
|
|||
| Former ID |
DNC005852
|
|||
| Drug Name |
3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol
|
|||
| Synonyms |
1-METHYLPSILOCIN; 1465-16-3; 3-[2-(DIMETHYLAMINO)ETHYL]-1-METHYLINDOL-4-OL; CHEMBL197664; 3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol; SCHEMBL12558828; CTK4C4996; DTXSID40658761; MolPort-023-276-636; ZINC13985099; BDBM50171261; AKOS024457385; API0007835; B7244; J-008232
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C13H18N2O
|
|||
| Canonical SMILES |
CN1C=C(C2=C1C=CC=C2O)CCN(C)C
|
|||
| InChI |
1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3
|
|||
| InChIKey |
MZZRFEIDRWKTKJ-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 1465-16-3
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
| 5-HT 2B receptor (HTR2B) | Target Info | Inhibitor | [1] | |
| 5-HT 2C receptor (HTR2C) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | SAR of psilocybin analogs: discovery of a selective 5-HT 2C agonist. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4555-9. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.