Drug Information
Drug General Information | Top | |||
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Drug ID |
D0S2OA
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Former ID |
DNC007500
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Drug Name |
1-benzhydryl-4-(benzyloxy)-4-phenylpiperidine
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Synonyms |
CHEMBL229018; 1-benzhydryl-4-(benzyloxy)-4-phenylpiperidine
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C31H31NO
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Canonical SMILES |
C1CN(CCC1(C2=CC=CC=C2)OCC3=CC=CC=C3)C(C4=CC=CC=C4)C5=CC=CC=C5
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InChI |
1S/C31H31NO/c1-5-13-26(14-6-1)25-33-31(29-19-11-4-12-20-29)21-23-32(24-22-31)30(27-15-7-2-8-16-27)28-17-9-3-10-18-28/h1-20,30H,21-25H2
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InChIKey |
KSNUQMXXRSKFOM-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Nociceptin receptor (OPRL1) | Target Info | Inhibitor | [1] |
Opioid receptor delta (OPRD1) | Target Info | Inhibitor | [1] | |
Opioid receptor kappa (OPRK1) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
cGMP-PKG signaling pathway | ||||
Sphingolipid signaling pathway | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
Enkephalin release | ||||
Opioid proenkephalin pathway | ||||
Opioid proopiomelanocortin pathway | ||||
Opioid prodynorphin pathway | ||||
Reactome | Peptide ligand-binding receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Peptide GPCRs | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Bioorg Med Chem Lett. 2007 Jun 1;17(11):3023-7. Epub 2007 Mar 23.Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 1. |
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