Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T1HY
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| Former ID |
DNC011645
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| Drug Name |
N-Hydroxy-3-naphthalen-2-yl-N-phenyl-acrylamide
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| Synonyms |
CHEMBL154575; N-Hydroxy-3-naphthalen-2-yl-N-phenyl-acrylamide; BDBM50015102; (E)-3-(2-Naphthalenyl)-N-phenyl-2-propenehydroxamic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C19H15NO2
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| Canonical SMILES |
C1=CC=C(C=C1)N(C(=O)C=CC2=CC3=CC=CC=C3C=C2)O
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| InChI |
1S/C19H15NO2/c21-19(20(22)18-8-2-1-3-9-18)13-11-15-10-12-16-6-4-5-7-17(16)14-15/h1-14,22H/b13-11+
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| InChIKey |
OSTLUPOHWIAJIK-ACCUITESSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Vitamin D Receptor Pathway | |||
| Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships. J Med Chem. 1990 Mar;33(3):992-8. | |||
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