Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T2MV
|
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| Former ID |
DNC000258
|
|||
| Drug Name |
AS-9705
|
|||
| Drug Type |
Small molecular drug
|
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| Indication | Gastric motility disorder [ICD-11: DA21; ICD-10: K22.4] | Investigative | [1] | |
| Vomiting [ICD-11: MD90; ICD-10: R11] | Investigative | [1] | ||
| Company |
Dainippon Pharmaceuticals
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C14H19NO3
|
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| Canonical SMILES |
CCOC(=O)C1=C(N(C(=C1C(=O)C)C)C2CC2)C
|
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| InChI |
1S/C14H19NO3/c1-5-18-14(17)13-9(3)15(11-6-7-11)8(2)12(13)10(4)16/h11H,5-7H2,1-4H3
|
|||
| InChIKey |
KUMRNXGGFLRUIV-UHFFFAOYSA-N
|
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| CAS Number |
CAS 423768-51-8
|
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dopamine D3 receptor (D3R) | Target Info | Antagonist | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Dopaminergic synapse | ||||
| Reactome | Dopamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| Nicotine Activity on Dopaminergic Neurons | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for chemotherapy-induced emesis. Expert Opin Emerg Drugs. 2006 Mar;11(1):137-51. | |||
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