Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0T5FY
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| Former ID |
DNC012411
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| Drug Name |
2,4-Dichloro-N-(4-phenyl-thiazol-2-yl)-benzamide
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| Synonyms |
CHEMBL61381; 2,4-Dichloro-N-(4-phenyl-1,3-thiazol-2-yl)benzamide; 260790-88-3; (Z)-2,4-dichloro-N-(4-phenylthiazol-2(3H)-ylidene)benzamide; 5307-12-0; AC1LCD3F; CBMicro_016815; Oprea1_161519; 2,4-Dichloro-N-(4-phenyl-thiazol-2-yl)-benzamide; ARONIS019647; KS-00004BJV; DTXSID00344799; MolPort-001-620-431; MWSDOEQEOIKHRL-UHFFFAOYSA-N; MolPort-003-009-221; ZINC4696587; CCG-5657; STK048438; BDBM50101786; AKOS000486711; AKOS024573981; MCULE-1720813827; ST036566; BIM-0016665.P001; N-(4-Phenyl-2-thiazolyl)-2,4-dichlorobenzamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H10Cl2N2OS
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3=C(C=C(C=C3)Cl)Cl
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| InChI |
1S/C16H10Cl2N2OS/c17-11-6-7-12(13(18)8-11)15(21)20-16-19-14(9-22-16)10-4-2-1-3-5-10/h1-9H,(H,19,20,21)
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| InChIKey |
MWSDOEQEOIKHRL-UHFFFAOYSA-N
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| CAS Number |
CAS 5307-12-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A1 receptor (ADORA1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| cAMP signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Morphine addiction | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| RANKL Signaling Pathway | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor. Bioorg Med Chem Lett. 2001 Aug 6;11(15):2017-9. | |||
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