Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T9ZQ
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| Former ID |
DNC013446
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| Drug Name |
5-chloro-1H-indazole
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| Synonyms |
5-Chloro-1H-indazole; 698-26-0; 1H-Indazole, 5-chloro-; 5-Chloroindazole; 5-CHLORO INDAZOLE; EINECS 211-812-1; NSC 78434; BRN 0003260; CHEMBL246746; FVNCILPDWNBPLK-UHFFFAOYSA-N; AK-23822; 5-chloro-indazole; 2H-Indazole, 5-chloro-; NSC78434; 5-chloro-2H-indazole; AC1L2CF8; 5-23-06-00175 (Beilstein Handbook Reference); 5-CHLORO(1H)INDAZOLE; SCHEMBL3540025; SCHEMBL16523221; CTK2F6769; DTXSID70220091; MolPort-000-002-983; 5-Chloro-1H-indazole, AldrichCPR; ZX-CM006597; ZX-AT013670; ZINC4876880; BCP00023; ACT10091; FCH837623; BDBM50209242
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H5ClN2
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| Canonical SMILES |
C1=CC2=C(C=C1Cl)C=NN2
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| InChI |
1S/C7H5ClN2/c8-6-1-2-7-5(3-6)4-9-10-7/h1-4H,(H,9,10)
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| InChIKey |
FVNCILPDWNBPLK-UHFFFAOYSA-N
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| CAS Number |
CAS 698-26-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nitric-oxide synthase brain (NOS1) | Target Info | Inhibitor | [1] |
| BioCyc | Citrulline-nitric oxide cycle | |||
| KEGG Pathway | Arginine and proline metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Phagosome | ||||
| Circadian entrainment | ||||
| Long-term depression | ||||
| Salivary secretion | ||||
| Alzheimer's disease | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Panther Pathway | CCKR signaling map ST | |||
| Pathwhiz Pathway | Arginine and Proline Metabolism | |||
| Reactome | ROS production in response to bacteria | |||
| Nitric oxide stimulates guanylate cyclase | ||||
| WikiPathways | Monoamine Transport | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
| Spinal Cord Injury | ||||
| Alzheimers Disease | ||||
| Effects of Nitric Oxide | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80. | |||
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