Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0TO3O
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| Drug Name |
PMID29671355-Compound-16
|
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| Drug Type |
Small molecular drug
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| Company |
FORMA THERAPEUTICS, INC
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H24N2O3
|
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| Canonical SMILES |
C1CC2(CCC3=C(C2)C=CC(=C3)C(=O)NO)C(=O)N(C1)CC4=CC=CC=C4
|
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| InChI |
1S/C22H24N2O3/c25-20(23-27)18-7-8-19-14-22(11-9-17(19)13-18)10-4-12-24(21(22)26)15-16-5-2-1-3-6-16/h1-3,5-8,13,27H,4,9-12,14-15H2,(H,23,25)
|
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| InChIKey |
PRTQLYSHPNDHIG-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histone deacetylase 6 (HDAC6) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Histone deacetylase 6 (HDAC6) | Target's Patent Info | [1] | |
| KEGG Pathway | Alcoholism | |||
| Viral carcinogenesis | ||||
| Pathway Interaction Database | Signaling events mediated by HDAC Class II | |||
| Signaling events mediated by HDAC Class I | ||||
| Reactome | NOTCH1 Intracellular Domain Regulates Transcription | |||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | ||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | ||||
| Assembly of the primary cilium | ||||
| WikiPathways | Ectoderm Differentiation | |||
| Neural Crest Differentiation | ||||
| Cell Cycle | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | HDAC inhibitors: a 2013-2017 patent survey.Expert Opin Ther Pat. 2018 Apr 19:1-17. | |||
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