Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0TZ1G
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| Former ID |
DAP000296
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| Drug Name |
Procaine
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| Synonyms |
Allocaine; Anticort; Anuject; Duracaine; Gerokit; Gerovital; Jenacain; Jenacaine; Nissocaine; Norocaine; Novocain; Novocaine; Procain; Procaina; Procainum; Scurocaine; Spinocaine; Solution of novocain; Factor H3; SP01; SP01A; Stoff H3; Vitamin H3; Anticort (TM); Diethylaminoethyl p-aminobenzoate; Gerovital H-3; Novocain (TN); P-Aminobenzoyldiethylaminoethanol; P-Aminobenzyoyldiethylaminoethanol; Procaina [INN-Spanish]; Procaine (INN); Procaine [INN:BAN]; Procaine, base; Procainum [INN-Latin]; SP-01A; Solution of novocain (TN); Beta-Diethylaminoethyl 4-aminobenzoate; P-Aminobenzoic acid 2-diethylaminoethyl ester; Beta-(Diethylamino)ethyl 4-aminobenzoate; Beta-(Diethylamino)ethyl p-aminobenzoate; BENZOIC ACID,4-AMINO,2-DIETHYLAMINOETHYL ESTER PROCAIN BASE; Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester; Benzoic acid, p-amino-, 2-(diethylamino)ethyl ester; 2-(Diethylamino)ethyl 4-aminobenzoate; 2-(Diethylamino)ethyl p-aminobenzoate; 2-(Diethylamino)ethyl-4-aminobenzoate; 2-Diethylaminoethyl 4-aminobenzoate; 2-Diethylaminoethyl p-aminobenzoate; 2-Diethylaminoethylester kyseliny p-aminobenzoove; 2-Diethylaminoethylester kyseliny p-aminobenzoove [Czech]; 4-Aminobenzoesaeure-beta-diethylaminoethylester; 4-Aminobenzoic acid 2-(diethylamino) ethyl ester; 4-Aminobenzoic acid diethylaminoethyl ester
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| Drug Type |
Small molecular drug
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| Indication | Anaesthesia [ICD-11: 9A78.6; ICD-10: Y48.3] | Approved | [1] | |
| Therapeutic Class |
Anesthetics
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| Company |
Wyeth Pharmaceuticals
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| Structure |
 |
Download2D MOL |
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| Formula |
C13H20N2O2
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| Canonical SMILES |
CCN(CC)CCOC(=O)C1=CC=C(C=C1)N
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| InChI |
1S/C13H20N2O2/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11/h5-8H,3-4,9-10,14H2,1-2H3
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| InChIKey |
MFDFERRIHVXMIY-UHFFFAOYSA-N
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| CAS Number |
CAS 59-46-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9579, 442275, 588149, 608576, 3138734, 5227621, 7980388, 8153025, 10528809, 11111696, 11111697, 11335295, 11360534, 11363732, 11366294, 11368856, 11371831, 11374114, 11377018, 11461506, 11466069, 11467189, 11485067, 11485818, 11489112, 11490372, 11492303, 11494652, 15196329, 29223992, 46507724, 47216639, 47440106, 47440107, 47588846, 48034960, 48259069, 48259070, 48259071, 49698882, 49885723, 50111197, 50612848, 53790362, 57304817, 57322521, 57820310, 85088908, 85788823, 90341175
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| ChEBI ID |
CHEBI:8430
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| ADReCS Drug ID | BADD_D01844 ; BADD_D01845 | |||
| SuperDrug ATC ID |
C05AD05; N01BA02; S01HA05
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| SuperDrug CAS ID |
cas=000059461
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 3A receptor (HTR3A) | Target Info | Antagonist | [2] |
| KEGG Pathway | Serotonergic synapse | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | 5HT3 type receptor mediated signaling pathway | |||
| Reactome | Ligand-gated ion channel transport | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Local anesthetics have different mechanisms and sites of action at recombinant 5-HT3 receptors. Reg Anesth Pain Med. 2007 Nov-Dec;32(6):462-70. | |||
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