Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0U3LS
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| Former ID |
DAP000244
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| Drug Name |
Triazolam
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| Synonyms |
Clorazolam; Halcion; Hypnostat; Novidorm; Novodorm; Songar; Triazolamum; Trilam; Apo Triazo; Apotex Brand of Triazolam; Gen Triazolam; Genpharm Brand of Triazolam; Gerard Brand of Triazolam; Pfizer Brand of Triazolam; Triazolam Pfizer Brand; TGAR01H; U 33030; Alti-Triazolam; Apo-Triazo; Gen-Triazolam; Halcion (TN); Halcion (triazolam); Hypam (TN); Novo-Triolam; Triazolamum [INN-Latin]; Trilam (TN); U 33,030; U-33030; U33,030; Apo-Triazo (TN); U-33,030; Triazolam (JAN/USP/INN); Triazolam [USAN:BAN:INN:JAN]; 8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-(1,2,4)triazolo(4,3-a)(1,4)benzodiazepine; 8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine; 8-Chloro-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine; 8-Chloro-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine; 8-Chloro-6-[2-chlorophenyl]-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
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| Drug Type |
Small molecular drug
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| Indication | Insomnia [ICD-11: 7A00-7A0Z] | Approved | [1], [2] | |
| Therapeutic Class |
Hypnotics and Sedatives
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| Company |
Upjohn Corporation
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| Structure |
 |
Download2D MOL |
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| Formula |
C17H12Cl2N4
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| Canonical SMILES |
CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4Cl
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| InChI |
1S/C17H12Cl2N4/c1-10-21-22-16-9-20-17(12-4-2-3-5-14(12)19)13-8-11(18)6-7-15(13)23(10)16/h2-8H,9H2,1H3
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| InChIKey |
JOFWLTCLBGQGBO-UHFFFAOYSA-N
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| CAS Number |
CAS 28911-01-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
5663633, 7847453, 7849624, 7980828, 8153415, 10517205, 12013397, 14875826, 24900602, 29214869, 29224597, 46509147, 50057244, 50113071, 53789234, 57322838, 58107043, 75839501, 85209509, 103189071, 103856603, 103916143, 104309572, 125536835, 128303523, 134337558, 134996744, 136949649, 137005119, 143051050, 144206170, 160964236, 164765748, 164765749, 175268086, 176262073, 178103886, 179116931, 184580915, 198991636, 210279816, 210282139, 223366877, 223454573, 224247842, 226416360, 250118403, 252357765
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| ChEBI ID |
CHEBI:9674
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| ADReCS Drug ID | BADD_D02277 | |||
| SuperDrug ATC ID |
N05CD05
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| SuperDrug CAS ID |
cas=028911015
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Translocator protein (TSPO) | Target Info | Modulator | [3] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| HTLV-I infection | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7313). | |||
| REF 2 | What every dentist should know about the "z-sedatives". J Mass Dent Soc. 2007 Fall;56(3):44-5. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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