Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0U3YB
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| Former ID |
DAP000913
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| Drug Name |
Masoprocol
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| Synonyms |
NDGA; N 5023; TNP00263; Actinex (TN); Nordihydroguaiaretic acid (meso-form); (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol; 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
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| Drug Type |
Small molecular drug
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| Indication | Prostate cancer [ICD-11: 2C82.0; ICD-10: C61; ICD-9: 185] | Approved | [1], [2] | |
| Therapeutic Class |
Anticancer Agents
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| Structure |
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Download2D MOL |
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| Formula |
C18H22O4
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| Canonical SMILES |
CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O
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| InChI |
1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3/t11-,12+
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| InChIKey |
HCZKYJDFEPMADG-TXEJJXNPSA-N
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| CAS Number |
CAS 27686-84-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
12902, 70634, 519564, 799650, 855767, 3156160, 5633842, 8149857, 8152791, 10524247, 11336174, 11361413, 11364040, 11364761, 11366602, 11367323, 11369164, 11369885, 11372925, 11375485, 11377326, 11378050, 11408384, 11462385, 11494960, 14800563, 24278590, 24886494, 26759213, 29204445, 29223625, 47216857, 47291213, 47365287, 47440357, 47885496, 49748321, 50037381, 50105253, 50105254, 53789186, 56370338, 56463284, 57322317, 57390614, 57652455, 57654453, 75686389, 81093171, 85088295
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| ChEBI ID |
CHEBI:73468
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| SuperDrug ATC ID |
L01XX10
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| SuperDrug CAS ID |
cas=027686846
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4265). | |||
| REF 2 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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