Drug Information
Drug General Information | Top | |||
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Drug ID |
D0UV6L
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Former ID |
DIB018216
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Drug Name |
[3H](S)-zacopride
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Synonyms |
[3H](S)-zacopride; GTPL4074
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C15H20ClN3O2
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Canonical SMILES |
COC1=CC(=C(C=C1C(=O)NC2CN3CCC2CC3)Cl)N
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InChI |
1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20)/t13-/m1/s1/i1T3
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InChIKey |
FEROPKNOYKURCJ-RYASAWMLSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 3A receptor (HTR3A) | Target Info | Antagonist | [2] |
KEGG Pathway | Serotonergic synapse | |||
NetPath Pathway | IL2 Signaling Pathway | |||
Panther Pathway | 5HT3 type receptor mediated signaling pathway | |||
Reactome | Ligand-gated ion channel transport | |||
WikiPathways | SIDS Susceptibility Pathways | |||
Iron uptake and transport |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4074). | |||
REF 2 | Autoradiographic distribution of [3H]-(S)-zacopride-labelled 5-HT3 receptors in human brain. J Neurol Sci. 1996 Dec;144(1-2):119-27. |
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