Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0W0QF
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| Former ID |
DNC012407
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| Drug Name |
4-Methyl-N-(4-phenyl-thiazol-2-yl)-benzamide
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| Synonyms |
4-Methyl-N-(4-phenyl-1,3-thiazol-2-yl)benzamide; CHEMBL294175; 4-Methyl-N-(4-phenyl-thiazol-2-yl)-benzamide; NERONVMZIDSIRT-UHFFFAOYSA-N; 87614-00-4; (Z)-4-methyl-N-(4-phenylthiazol-2(3H)-ylidene)benzamide; AC1Q2JVA; AC1LB6OY; Oprea1_598164; Oprea1_751162; Oprea1_000114; SCHEMBL233522; ARONIS019641; 2-[(4-methylphenyl)carboxamido]-4-phenyl-1,3-thiazole; KS-00004BJP; MolPort-003-009-217; MolPort-001-029-741; ZINC4031557; BDBM50101781; STK084905; AKOS024573976; AKOS000486758; MCULE-8350259880; ST036564
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H14N2OS
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| Canonical SMILES |
CC1=CC=C(C=C1)C(=O)NC2=NC(=CS2)C3=CC=CC=C3
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| InChI |
1S/C17H14N2OS/c1-12-7-9-14(10-8-12)16(20)19-17-18-15(11-21-17)13-5-3-2-4-6-13/h2-11H,1H3,(H,18,19,20)
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| InChIKey |
NERONVMZIDSIRT-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A1 receptor (ADORA1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| cAMP signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Morphine addiction | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| RANKL Signaling Pathway | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor. Bioorg Med Chem Lett. 2001 Aug 6;11(15):2017-9. | |||
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