Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0W4OL
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| Former ID |
DNC003629
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| Drug Name |
FK-633
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| Synonyms |
FK-633; Dryofragin; ((4-(4-Amidinophenoxy)butanoyl)aspartyl)valine; 147865-49-4; CHEMBL34901; FK 633; AC1L31M0; SCHEMBL1710973; DTXSID00163821; ZINC3918297; BDBM50092111; LS-161294; FR-144633; 4-(4-amidinophenoxy)butanoyl-aspartyl-valine; 2-{2-[4-(4-Carbamimidoyl-phenoxy)-butyrylamino]-3-carboxy-propionylamino}-3-methyl-butyric acid (FK633); (2S)-2-[[(2S)-2-[4-(4-carbamimidoylphenoxy)butanoylamino]-4-hydroxy-4-oxobutanoyl]amino]-3-methylbutanoic acid
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| Drug Type |
Small molecular drug
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| Indication | Artery stenosis [ICD-11: BD52; ICD-10: I51.89] | Discontinued in Phase 2 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H28N4O7
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| Canonical SMILES |
CC(C)C(C(=O)O)NC(=O)C(CC(=O)O)NC(=O)CCCOC1=CC=C(C=C1)C(=N)N
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| InChI |
1S/C20H28N4O7/c1-11(2)17(20(29)30)24-19(28)14(10-16(26)27)23-15(25)4-3-9-31-13-7-5-12(6-8-13)18(21)22/h5-8,11,14,17H,3-4,9-10H2,1-2H3,(H3,21,22)(H,23,25)(H,24,28)(H,26,27)(H,29,30)/t14-,17-/m0/s1
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| InChIKey |
JFCXCBBSUORTNS-YOEHRIQHSA-N
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| CAS Number |
CAS 147865-49-4
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006561) | |||
| REF 2 | Efficacy of FK633, an ultra-short acting glycoprotein IIb/IIIa antagonist on platelet preservation during and after cardiopulmonary bypass. Eur J Cardiothorac Surg. 2004 Aug;26(2):289-93. | |||
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