Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0W6KM
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| Former ID |
DIB005600
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| Drug Name |
Dasotraline
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| Synonyms |
SEP-225289; SEP-289; Triple reuptake inhibitors (depression), Sepracor
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| Drug Type |
Small molecular drug
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| Indication | Attention deficit hyperactivity disorder [ICD-11: 6A05.Z; ICD-9: 314] | Approved | [1] | |
| Eating disorder [ICD-11: 6B82; ICD-10: F50, F98.2] | Phase 3 | [1] | ||
| Mood disorder [ICD-11: 6A60-6E23] | Phase 3 | [2], [3] | ||
| Company |
Sunovion pharmaceuticals
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| Structure |
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Download2D MOL |
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| Formula |
C16H15Cl2N
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| Canonical SMILES |
C1CC(C2=CC=CC=C2C1C3=CC(=C(C=C3)Cl)Cl)N
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| InChI |
1S/C16H15Cl2N/c17-14-7-5-10(9-15(14)18)11-6-8-16(19)13-4-2-1-3-12(11)13/h1-5,7,9,11,16H,6,8,19H2/t11-,16+/m0/s1
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| InChIKey |
SRPXSILJHWNFMK-MEDUHNTESA-N
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| CAS Number |
CAS 675126-05-3
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8308). | |||
| REF 3 | ClinicalTrials.gov (NCT02276209) Dasotraline Adult ADHD Study. U.S. National Institutes of Health. | |||
| REF 4 | Dasotraline for the Treatment of Attention-Deficit/Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled, Proof-of-Concept Trial in Adults. Neuropsychopharmacology. 2015 Nov;40(12):2745-52. | |||
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