Drug Information
Drug General Information | Top | |||
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Drug ID |
D0W8EB
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Former ID |
DNC005860
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Drug Name |
3-(3-Dimethylamino-propyl)-1H-indol-4-ol
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Synonyms |
CHEMBL198617; 3-(3-Dimethylamino-propyl)-1H-indol-4-ol
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C13H18N2O
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Canonical SMILES |
CN(C)CCCC1=CNC2=C1C(=CC=C2)O
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InChI |
1S/C13H18N2O/c1-15(2)8-4-5-10-9-14-11-6-3-7-12(16)13(10)11/h3,6-7,9,14,16H,4-5,8H2,1-2H3
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InChIKey |
IBSZSSDQXMYZOZ-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
5-HT 2B receptor (HTR2B) | Target Info | Inhibitor | [1] | |
5-HT 2C receptor (HTR2C) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
Serotonin Receptor 2 and STAT3 Signaling | ||||
SIDS Susceptibility Pathways | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | SAR of psilocybin analogs: discovery of a selective 5-HT 2C agonist. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4555-9. |
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