Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0W9UV
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| Former ID |
DNC008850
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| Drug Name |
2-amino-4,6-dimethylpyridine
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| Synonyms |
2-AMINO-4,6-DIMETHYLPYRIDINE; 5407-87-4; 4,6-dimethylpyridin-2-amine; 6-Amino-2,4-lutidine; 2-Pyridinamine, 4,6-dimethyl-; 4,6-Dimethyl-2-pyridinamine; 4,6-Dimethyl-2-pyridylamine; Pyridine, 2-amino-4,6-dimethyl-; 2,4-Lutidine, 6-amino-; NSC 10731; 2-Amino-4,6-dimehtylpyridine; EINECS 226-470-9; UNII-7NVZ9DW9Q5; BRN 0002048; 7NVZ9DW9Q5; CHEMBL59925; 4,6-Dimethyl-2-aminopyridine; 2-amino-4,6-dimethyl pyridine; 4,6-Dimethyl-pyridin-2-ylamine; BRBUBVKGJRPRRD-UHFFFAOYSA-N; 2-Amino-4,6-dimethylpyridine, 99%; PubChem19956; AC1Q2ICQ
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H10N2
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| Canonical SMILES |
CC1=CC(=NC(=C1)N)C
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| InChI |
1S/C7H10N2/c1-5-3-6(2)9-7(8)4-5/h3-4H,1-2H3,(H2,8,9)
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| InChIKey |
BRBUBVKGJRPRRD-UHFFFAOYSA-N
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| CAS Number |
CAS 5407-87-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nitric-oxide synthase brain (NOS1) | Target Info | Inhibitor | [1] |
| BioCyc | Citrulline-nitric oxide cycle | |||
| KEGG Pathway | Arginine and proline metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Phagosome | ||||
| Circadian entrainment | ||||
| Long-term depression | ||||
| Salivary secretion | ||||
| Alzheimer's disease | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Panther Pathway | CCKR signaling map ST | |||
| Pathwhiz Pathway | Arginine and Proline Metabolism | |||
| Reactome | ROS production in response to bacteria | |||
| Nitric oxide stimulates guanylate cyclase | ||||
| WikiPathways | Monoamine Transport | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Amyotrophic lateral sclerosis (ALS) | ||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
| Spinal Cord Injury | ||||
| Alzheimers Disease | ||||
| Effects of Nitric Oxide | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | L337H mutant of rat neuronal nitric oxide synthase resembles human neuronal nitric oxide synthase toward inhibitors. J Med Chem. 2009 Jul 23;52(14):4533-7. | |||
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