Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0WA9U
|
|||
Drug Name |
PMID29649907-Compound-1
|
|||
Drug Type |
Small molecular drug
|
|||
Company |
INTERCEPT PHARMACEUTICALS, INC
|
|||
Structure |
Download2D MOL |
|||
Formula |
C26H44O4
|
|||
Canonical SMILES |
CCC1C2CCCCC2(C3C(CC4(C(C3C1O)CCC4C(C)CCC(=O)O)C)O)C
|
|||
InChI |
1S/C26H44O4/c1-5-16-18-8-6-7-13-25(18,3)23-20(27)14-26(4)17(15(2)9-12-21(28)29)10-11-19(26)22(23)24(16)30/h15-20,22-24,27,30H,5-14H2,1-4H3,(H,28,29)/t15-,16-,17-,18+,19?,20+,22?,23?,24-,25+,26-/m1/s1
|
|||
InChIKey |
IMDDBKRWRHUMNT-QAUCXMOESA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Farnesoid X-activated receptor (FXR) | Target Info | Agonist | [1] |
Target's Patent Info | Farnesoid X-activated receptor (FXR) | Target's Patent Info | [1] | |
KEGG Pathway | Bile secretion | |||
Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptor | |||
Reactome | Recycling of bile acids and salts | |||
PPARA activates gene expression | ||||
Endogenous sterols | ||||
WikiPathways | Nuclear Receptors in Lipid Metabolism and Toxicity | |||
Nuclear Receptors Meta-Pathway | ||||
Farnesoid X Receptor Pathway | ||||
Drug Induction of Bile Acid Pathway |
References | Top | |||
---|---|---|---|---|
REF 1 | Farnesoid X receptor modulators 2014-present: a patent review.Expert Opin Ther Pat. 2018 May;28(5):351-364. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.