Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0WW1K
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| Former ID |
DNC000044
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| Drug Name |
2-(4-hydroxylphenyl)-3-(3,5-dihydroxylphenyl) propenoic acid (NNU-hdpa)
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| Synonyms |
ZINC34018202; (E)-alpha-(4-Hydroxyphenyl)-3,5-dihydroxycinnamic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C15H12O5
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| Canonical SMILES |
C1=CC(=CC=C1C(=CC2=CC(=CC(=C2)O)O)C(=O)O)O
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| InChI |
1S/C15H12O5/c16-11-3-1-10(2-4-11)14(15(19)20)7-9-5-12(17)8-13(18)6-9/h1-8,16-18H,(H,19,20)/b14-7+
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| InChIKey |
LGVSCQYCQUYTOK-VGOFMYFVSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Vitamin D Receptor Pathway | |||
| Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Anti-inflammatory effects and gastrointestinal safety of NNU-hdpa, a novel dual COX/5-LOX inhibitor. Eur J Pharmacol. 2009 Jun 2;611(1-3):100-6. | |||
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