Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0X4CI
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| Former ID |
DNC005187
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| Drug Name |
2,3,4,5-Tetrabromo-6-(2,4-dibromo-phenoxy)-phenol
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| Synonyms |
CHEMBL362761; Phenol, 2,3,4,5-tetrabromo-6-(2,4-dibromophenoxy)-; 111863-67-3; ACMC-20meye; 2,3,4,5-tetrabromo-6-(2,4-dibromophenoxy)phenol; 2,3,4,5-Tetrabromo-6-(2,4-dibromo-phenoxy)-phenol; CTK0G1675; DTXSID50433647; BDBM50150785; 2,2',3,4,4',5-Hexabromo-6-hydroxydiphenyl ether; 2,3,4,5-tetrabromo-6-(2',4'-dibromophenoxy)phenol; 2-(2'',4''-dibromophenoxy-3,4,5,6-tetrabromophenol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H4Br6O2
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| Canonical SMILES |
C1=CC(=C(C=C1Br)Br)OC2=C(C(=C(C(=C2Br)Br)Br)Br)O
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| InChI |
1S/C12H4Br6O2/c13-4-1-2-6(5(14)3-4)20-12-10(18)8(16)7(15)9(17)11(12)19/h1-3,19H
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| InChIKey |
LDMKXEGTHGJWLG-UHFFFAOYSA-N
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| CAS Number |
CAS 111863-67-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 12-lipoxygenase (12-LOX) | Target Info | Inhibitor | [1] |
| Arachidonate 15-lipoxygenase (15-LOX) | Target Info | Inhibitor | [1] | |
| BioCyc | Resolvin D biosynthesis | |||
| Lipoxin biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Linoleic acid metabolism | ||||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. J Med Chem. 2004 Jul 29;47(16):4060-5. | |||
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