Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0X4RC
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| Former ID |
DNC011899
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| Drug Name |
PHENYLPIPERAZINE
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| Synonyms |
1-PHENYLPIPERAZINE; 92-54-6; N-Phenylpiperazine; Phenylpiperazine; Piperazine, 1-phenyl-; 1-Phenyl-piperazine; 1-Fenylpiperazin [Czech]; UNII-J9225CBI7D; n-phenyl piperazine; 1-phenyl piperazine; CCRIS 4334; N-Phenyldiethylenediamine; EINECS 202-165-6; BRN 0132157; CHEMBL9434; AI3-26332; J9225CBI7D; YZTJYBJCZXZGCT-UHFFFAOYSA-N; MFCD00005957; 1-Phenylpiperazine, 97%; 1-Fenylpiperazin; N-phenylpiperazin; N-PHENYLPIPERAZINE HYDROCHLORIDE; 1-phenylpiperazinehydrochloride; phenyl piperazine; phenyl-piperazine; N-phenylpyperazine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C10H14N2
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| Canonical SMILES |
C1CN(CCN1)C2=CC=CC=C2
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| InChI |
1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2
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| InChIKey |
YZTJYBJCZXZGCT-UHFFFAOYSA-N
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| CAS Number |
CAS 92-54-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Inhibitor | [1] |
| 5-HT 1D receptor (HTR1D) | Target Info | Inhibitor | [1] | |
| 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Calcium signaling pathway | ||||
| Gap junction | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| 5HT1 type receptor mediated signaling pathway | ||||
| 5HT2 type receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | |||
| G alpha (i) signalling events | ||||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| Serotonin Receptor 2 and STAT3 Signaling | ||||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 5-HT1 and 5-HT2 binding characteristics of some quipazine analogues. J Med Chem. 1986 Nov;29(11):2375-80. | |||
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