Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0X5SJ
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| Former ID |
DNAP001482
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| Drug Name |
Alacepril
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| Synonyms |
Cetapril (TN)
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| Drug Type |
Small molecular drug
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| Indication | Cardiovascular disease [ICD-11: BA00-BE2Z; ICD-10: I00-I99] | Approved | [1] | |
| Company |
Dainippon
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H26N2O5S
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| Canonical SMILES |
CC(CSC(=O)C)C(=O)N1CCCC1C(=O)NC(CC2=CC=CC=C2)C(=O)O
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| InChI |
1S/C20H26N2O5S/c1-13(12-28-14(2)23)19(25)22-10-6-9-17(22)18(24)21-16(20(26)27)11-15-7-4-3-5-8-15/h3-5,7-8,13,16-17H,6,9-12H2,1-2H3,(H,21,24)(H,26,27)/t13-,16+,17+/m1/s1
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| InChIKey |
FHHHOYXPRDYHEZ-COXVUDFISA-N
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| CAS Number |
CAS 74258-86-9
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7848962, 8194954, 12012862, 15451107, 43128232, 50006743, 50442755, 57318468, 99031293, 103095512, 103157165, 104351820, 117570221, 119525747, 124772209, 124893756, 127327732, 127327733, 127327734, 127327735, 127327736, 127847193, 135029396, 135377129, 137189513, 137231960, 141323946, 144206457, 152056074, 160697856, 163693475, 164814629, 179151063, 184545374, 187072450, 198968997, 223554738, 223914456, 226421005, 241134090, 252214694, 252359200
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| ChEBI ID |
CHEBI:31182
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Angiotensin-converting enzyme (ACE) | Target Info | Modulator | [2], [3] |
| KEGG Pathway | Renin-angiotensin system | |||
| Chagas disease (American trypanosomiasis) | ||||
| Hypertrophic cardiomyopathy (HCM) | ||||
| Pathwhiz Pathway | Angiotensin Metabolism | |||
| Reactome | Metabolism of Angiotensinogen to Angiotensins | |||
| WikiPathways | ACE Inhibitor Pathway | |||
| Metabolism of Angiotensinogen to Angiotensins | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. | |||
| REF 3 | Natural products in drug discovery and development. J Nat Prod. 1997 Jan;60(1):52-60. | |||
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