Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0XJ6D
|
|||
| Former ID |
DNC003598
|
|||
| Drug Name |
4-(3-Methyl-indole-1-sulfonyl)-phenylamine
|
|||
| Synonyms |
CHEMBL328816; SCHEMBL14642142; BDBM34150; n1-(4-aminobenzenesulfonyl)skatole; N-arenesulfonylindole antagonist, 9; 4-(3-methyl-1H-indole-1-sulfonyl)aniline, 8
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C15H14N2O2S
|
|||
| Canonical SMILES |
CC1=CN(C2=CC=CC=C12)S(=O)(=O)C3=CC=C(C=C3)N
|
|||
| InChI |
1S/C15H14N2O2S/c1-11-10-17(15-5-3-2-4-14(11)15)20(18,19)13-8-6-12(16)7-9-13/h2-10H,16H2,1H3
|
|||
| InChIKey |
ZNRJXSHXWJKTGJ-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 6 receptor (HTR6) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Pathwhiz Pathway | Excitatory Neural Signalling Through 5-HTR 6 and Serotonin | |||
| Reactome | Serotonin receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1707-11. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.