Drug Information
Drug General Information | Top | |||
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Drug ID |
D0YB3X
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Former ID |
DNC012403
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Drug Name |
3-Chloro-N-(4-phenyl-thiazol-2-yl)-benzamide
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Synonyms |
3-Chloro-N-(4-phenyl-thiazol-2-yl)-benzamide; CHEMBL61222; AC1LFIX3; Oprea1_263322; Oprea1_095427; SCHEMBL2754070; 2-[(3-chlorophenyl)carboxamido]-4-phenyl-1,3-thiazole; OHXHEHNTSIBWMV-UHFFFAOYSA-N; MolPort-001-997-617; ZINC208080; BDBM50101789; AKOS000651093; MCULE-4878334658; BAS 04456777; 50591-72-5; N-(4-Phenyl-2-thiazolyl)-3-chlorobenzamide
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H11ClN2OS
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Canonical SMILES |
C1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3=CC(=CC=C3)Cl
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InChI |
1S/C16H11ClN2OS/c17-13-8-4-7-12(9-13)15(20)19-16-18-14(10-21-16)11-5-2-1-3-6-11/h1-10H,(H,18,19,20)
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InChIKey |
OHXHEHNTSIBWMV-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Adenosine A1 receptor (ADORA1) | Target Info | Inhibitor | [1] |
KEGG Pathway | cGMP-PKG signaling pathway | |||
cAMP signaling pathway | ||||
Sphingolipid signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Morphine addiction | ||||
NetPath Pathway | TCR Signaling Pathway | |||
RANKL Signaling Pathway | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
Reactome | Adenosine P1 receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Nucleotide GPCRs | |||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor. Bioorg Med Chem Lett. 2001 Aug 6;11(15):2017-9. |
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