Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0YE5K
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| Former ID |
DNC011504
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| Drug Name |
N-(3-Phenyl-[1,2,4]thiadiazol-5-yl)-benzamide
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| Synonyms |
N-(3-phenyl-1,2,4-thiadiazol-5-yl)benzamide; CHEMBL165783; AC1M3OE0; N-(3-Phenyl-[1,2,4]thiadiazol-5-yl)-benzamide; MolPort-000-646-915; HMS3451M02; ZINC2889428; STL202734; BDBM50097440; AKOS000813205; MCULE-2440953367; UPCMLD0ENAT5889812:001; ST45223360; VU0618368-1; N-(3-Phenyl-1,2,4-thiadiazole-5-yl)benzamide; phenyl-N-(3-phenyl(1,2,4-thiadiazol-5-yl))carboxamide; F3394-1092
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H11N3OS
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| Canonical SMILES |
C1=CC=C(C=C1)C2=NSC(=N2)NC(=O)C3=CC=CC=C3
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| InChI |
1S/C15H11N3OS/c19-14(12-9-5-2-6-10-12)17-15-16-13(18-20-15)11-7-3-1-4-8-11/h1-10H,(H,16,17,18,19)
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| InChIKey |
AYSLYXJUYHXKHV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A2a receptor (ADORA2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Rap1 signaling pathway | |||
| Calcium signaling pathway | ||||
| cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Vascular smooth muscle contraction | ||||
| Parkinson's disease | ||||
| Alcoholism | ||||
| Pathwhiz Pathway | Intracellular Signalling Through Adenosine Receptor A2a and Adenosine | |||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | |||
| Reactome | NGF-independant TRKA activation | |||
| Adenosine P1 receptors | ||||
| G alpha (s) signalling events | ||||
| Surfactant metabolism | ||||
| WikiPathways | Nucleotide GPCRs | |||
| Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| NGF signalling via TRKA from the plasma membrane | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists. J Med Chem. 2001 Mar 1;44(5):749-62. | |||
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