Drug Information
Drug General Information | Top | |||
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Drug ID |
D0YG1E
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Former ID |
DNC011952
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Drug Name |
Etisulergine
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Synonyms |
Etisulergine; UNII-28N73Q6O7Y; 64795-23-9; 28N73Q6O7Y; Etisulerginum; Etisulergina; etisulergine[inn]; Etisulergine [INN]; Etisulerginum [INN-Latin]; Etisulergina [INN-Spanish]; CQ 32-084; AC1L2AKJ; AC1Q6V8T; SCHEMBL219311; CHEMBL38992; BDBM50225361; 72782-54-8 (mono-hydrochloride)
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C19H28N4O2S
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Canonical SMILES |
CCN(CC)S(=O)(=O)NC1CC2C(CC3=CNC4=CC=CC2=C34)N(C1)C
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InChI |
1S/C19H28N4O2S/c1-4-23(5-2)26(24,25)21-14-10-16-15-7-6-8-17-19(15)13(11-20-17)9-18(16)22(3)12-14/h6-8,11,14,16,18,20-21H,4-5,9-10,12H2,1-3H3/t14-,16+,18+/m0/s1
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InChIKey |
YHEIHLVIKSTGJE-YXJHDRRASA-N
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CAS Number |
CAS 64795-23-9
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Inhibitor | [1] |
5-HT 1D receptor (HTR1D) | Target Info | Inhibitor | [1] | |
5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] | |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Serotonergic synapse | ||||
Calcium signaling pathway | ||||
Gap junction | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
5HT1 type receptor mediated signaling pathway | ||||
5HT2 type receptor mediated signaling pathway | ||||
Reactome | Serotonin receptors | |||
G alpha (i) signalling events | ||||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
SIDS Susceptibility Pathways | ||||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
Serotonin Receptor 2 and STAT3 Signaling | ||||
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | Resolution and absolute configuration of the potent dopamine agonist N,N-diethyl-N'-[(3 alpha, 4a alpha, 10a beta)-1,2,3,4,4a,5,10,10a- -octahydro-... J Med Chem. 1985 Oct;28(10):1540-2. |
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