Drug Information
Drug General Information | Top | |||
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Drug ID |
D0YJ9T
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Former ID |
DIB004400
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Drug Name |
DU-6681
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Synonyms |
DU-6681a (Na salt); (1R,5S,6S)-2-[6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-6(S)-ylsulfanyl]-6-[1(R)-hydroxyethyl]-1-methyl-1-carba-2-penem-3-carboxylic acid
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Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Discontinued in Phase 1 | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H19N3O4S
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Canonical SMILES |
CC1C2C(C(=O)N2C(=C1SC3CC4=NC=CN4C3)C(=O)O)C(C)O
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InChI |
1S/C16H19N3O4S/c1-7-12-11(8(2)20)15(21)19(12)13(16(22)23)14(7)24-9-5-10-17-3-4-18(10)6-9/h3-4,7-9,11-12,20H,5-6H2,1-2H3,(H,22,23)/t7-,8-,9+,11-,12+/m1/s1
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InChIKey |
SYFIHQJVKJGGGB-VZSYODPGSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Bacterial Penicillin binding protein (Bact PBP) | Target Info | Modulator | [2] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006219) | |||
REF 2 | Pharmacokinetics and Safety of Ascending Single Doses of DZ-2640, a New Oral Carbapenem Antibiotic, Administered to Healthy Japanese Subjects. Antimicrob Agents Chemother. 2000 March; 44(3): 578-582. |
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