Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0YK9Q
|
|||
Drug Name |
PMID29649907-Compound-37
|
|||
Drug Type |
Small molecular drug
|
|||
Company |
ALIOS BIOPHARMA, INC
|
|||
Structure |
Download2D MOL |
|||
Formula |
C24H23F2N3O3
|
|||
Canonical SMILES |
CC(C)OC(=O)C1=CN(CC(C2=C1NC3=C2N=CC=C3)(C)C)C(=O)C4=CC(=C(C=C4)F)F
|
|||
InChI |
1S/C24H23F2N3O3/c1-13(2)32-23(31)15-11-29(22(30)14-7-8-16(25)17(26)10-14)12-24(3,4)19-20(15)28-18-6-5-9-27-21(18)19/h5-11,13,28H,12H2,1-4H3
|
|||
InChIKey |
LHMOWNHVOCSXKQ-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Farnesoid X-activated receptor (FXR) | Target Info | Agonist | [1] |
Target's Patent Info | Farnesoid X-activated receptor (FXR) | Target's Patent Info | [1] | |
KEGG Pathway | Bile secretion | |||
Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptor | |||
Reactome | Recycling of bile acids and salts | |||
PPARA activates gene expression | ||||
Endogenous sterols | ||||
WikiPathways | Nuclear Receptors in Lipid Metabolism and Toxicity | |||
Nuclear Receptors Meta-Pathway | ||||
Farnesoid X Receptor Pathway | ||||
Drug Induction of Bile Acid Pathway |
References | Top | |||
---|---|---|---|---|
REF 1 | Farnesoid X receptor modulators 2014-present: a patent review.Expert Opin Ther Pat. 2018 May;28(5):351-364. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.