Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Z7XI
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| Former ID |
DNC012482
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| Drug Name |
3-Methyl-1,2,3,4-tetrahydro-isoquinoline
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| Synonyms |
3-Methyl-1,2,3,4-tetrahydroisoquinoline; 29726-60-1; 1,2,3,4-Tetrahydro-3-methylisoquinoline; Isoquinoline, 1,2,3,4-tetrahydro-3-methyl-; 3-Methyl-1,2,3,4-tetrahydro-isoquinoline; CHEMBL60434; UEKQPSAKUNXFHL-UHFFFAOYSA-N; BAS 03334621; AC1Q1HKS; AC1LC3M2; SCHEMBL1011182; SCHEMBL15334650; KS-00000JVD; MolPort-001-990-837; HMS1698C16; BDBM50023304; ANW-75096; AKOS016843414; AKOS000650337; AB30586; NE31770; MCULE-3517571472; NCGC00184271-01; DA-07231; KB-70931; BS-13528; TC-163841; ST24042290; FT-0729461; EN300-86328
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H13N
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| Canonical SMILES |
CC1CC2=CC=CC=C2CN1
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| InChI |
1S/C10H13N/c1-8-6-9-4-2-3-5-10(9)7-11-8/h2-5,8,11H,6-7H2,1H3
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| InChIKey |
UEKQPSAKUNXFHL-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor alpha-2A (ADRA2A) | Target Info | Inhibitor | [1] |
| Adrenergic receptor alpha-2B (ADRA2B) | Target Info | Inhibitor | [1] | |
| Adrenergic receptor alpha-2C (ADRA2C) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Panther Pathway | Alpha adrenergic receptor signaling pathway | |||
| Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Reactome | Adrenoceptors | |||
| Adrenaline signalling through Alpha-2 adrenergic receptor | ||||
| Adrenaline,noradrenaline inhibits insulin secretion | ||||
| G alpha (i) signalling events | ||||
| G alpha (z) signalling events | ||||
| Surfactant metabolism | ||||
| WikiPathways | Monoamine GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Platelet Aggregation (Plug Formation) | ||||
| Integration of energy metabolism | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
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| REF 1 | Effect of ring size or an additional heteroatom on the potency and selectivity of bicyclic benzylamine-type inhibitors of phenylethanolamine N-meth... J Med Chem. 1996 Aug 30;39(18):3539-46. | |||
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