Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Z9VB
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Former ID |
DAP000679
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Drug Name |
Halazepam
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Synonyms |
Halazepamum; Pacinone; Paxipam; Sch 12041; Schering 12041; Alapryl (TN); Halazepamum [INN-Latin]; Pacinone (TN); Paxipam (TN); Sch-12041; Halazepam (USAN/INN); Halazepam [USAN:BAN:INN]; 7-Chloro-1,3-dihydro-5-phenyl-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepin-2-one; 7-Chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-2-one; 7=Chlor-5-phenyl-1-(2,2,2-trifluorethyl)-1H-1,4-benzodiazepin-2(3H)-on
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Drug Type |
Small molecular drug
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Indication | Anxiety disorder [ICD-11: 6B00-6B0Z; ICD-10: R45.0] | Approved | [1], [2] | |
Therapeutic Class |
Antianxiety Agents
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Structure |
Download2D MOL |
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Formula |
C17H12ClF3N2O
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Canonical SMILES |
C1C(=O)N(C2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3)CC(F)(F)F
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InChI |
1S/C17H12ClF3N2O/c18-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)22-9-15(24)23(14)10-17(19,20)21/h1-8H,9-10H2
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InChIKey |
WYCLKVQLVUQKNZ-UHFFFAOYSA-N
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CAS Number |
CAS 23092-17-3
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PubChem Compound ID | ||||
PubChem Substance ID |
6594591, 7847404, 7849649, 7979512, 8172307, 10514540, 12013412, 15447516, 34673752, 46508415, 48416077, 49884218, 50523071, 57311257, 58108214, 103252287, 104311411, 117505277, 125823332, 126666085, 129651092, 134223125, 134337968, 134994198, 137005588, 137440703, 137783727, 160964143, 163357042, 164842074, 178103770, 179150194, 198946459, 198993239, 223665073, 226458192, 250120434, 252350341
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ChEBI ID |
CHEBI:5603
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SuperDrug ATC ID |
N05BA13
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SuperDrug CAS ID |
cas=023092173
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Target and Pathway | Top | |||
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Target(s) | Translocator protein (TSPO) | Target Info | Modulator | [3] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
HTLV-I infection |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7195). | |||
REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 017736. | |||
REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. |
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