Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0ZC8K
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| Former ID |
DNC014300
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| Drug Name |
3,5-di(pyridin-4-yl)-1H-1,2,4-triazole
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| Synonyms |
4329-78-6; CHEMBL1078978; 4,4'-(1H-1,2,4-triazole-3,5-diyl)dipyridine; 3,5-DI(4-pyridyl)-1,2,4-triazole; 3,5-bis(pyridin-4-yl)-1,2,4-triazole; AC1M7KCV; 3,5-di(pyridin-4-yl)-1H-1,2,4-triazole; MLS000999673; 4-(3-pyridin-4-yl-1H-1,2,4-triazol-5-yl)pyridine; SCHEMBL10000033; CTK1D2724; QUKGHTHKDNHSOX-UHFFFAOYSA-; DTXSID00368692; QUKGHTHKDNHSOX-UHFFFAOYSA-N; MolPort-000-263-064; ZINC8048404; BDBM50311280; STK246494; AKOS002269457; AKOS001080808; MCULE-5677308017; 3,5-bis(4-pyridyl)-1,2,4-triazole; SMR000498789; ST092086
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H9N5
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| Canonical SMILES |
C1=CN=CC=C1C2=NC(=NN2)C3=CC=NC=C3
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| InChI |
1S/C12H9N5/c1-5-13-6-2-9(1)11-15-12(17-16-11)10-3-7-14-8-4-10/h1-8H,(H,15,16,17)
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| InChIKey |
QUKGHTHKDNHSOX-UHFFFAOYSA-N
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| CAS Number |
CAS 4329-78-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Xanthine dehydrogenase/oxidase (XDH) | Target Info | Inhibitor | [1] |
| BioCyc | Purine nucleotides degradation | |||
| Urate biosynthesis/inosine 5'-phosphate degradation | ||||
| Guanosine nucleotides degradation | ||||
| Adenosine nucleotides degradation | ||||
| Retinoate biosynthesis II | ||||
| KEGG Pathway | Purine metabolism | |||
| Caffeine metabolism | ||||
| Drug metabolism - other enzymes | ||||
| Metabolic pathways | ||||
| Peroxisome | ||||
| Panther Pathway | Adenine and hypoxanthine salvage pathway | |||
| Purine metabolism | ||||
| Pathwhiz Pathway | Caffeine Metabolism | |||
| Purine Metabolism | ||||
| Reactome | Purine catabolism | |||
| WikiPathways | Oxidative Stress | |||
| Effects of Nitric Oxide | ||||
| Metabolism of nucleotides | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of 3-(2-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole, FYX-051 - a xanthine oxidoreductase inhibitor for the treatment of hyperuricemia [... Bioorg Med Chem Lett. 2009 Nov 1;19(21):6225-9. | |||
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