Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D7KRB9
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| Drug Name |
Selnoflast
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| Synonyms |
Selnoflast; Selnoflast [INN]; Selnoflast [USAN]; T23RPA8WA2; RO7486967; Selnoflast [USAN:INN]; RG6418; 2260969-36-4; UNII-T23RPA8WA2; WHO 11687; RO-7486967; 1-Ethyl-N-(((1,2,3,5,6,7-hexahydro-S-indacen-4-yl)amino)carbonyl)-4-piperidinesulfonamide; 1-ethyl-N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]piperidine-4-sulfonamide; CHEMBL5095423; SCHEMBL20634304; GTPL12173; MFCD34579587; RG-6418; Example 6 [WO2019008025A1]; MS-26540; SY347075; HY-132831; CS-0204138; 1-(1-ethylpiperidin-4-yl)sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea; 4-Piperidinesulfonamide, 1-ethyl-N-(((1,2,3,5,6,7-hexahydro-S-indacen-4-yl)amino)carbonyl)-; 4-Piperidinesulfonamide,1-ethyl-N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-
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| Drug Type |
Small molecule
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| Indication | Inflammation [ICD-11: 1A00-CA43.1] | Phase 1 | [1] | |
| Company |
Roche
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| Structure |
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Download2D MOL |
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| Formula |
C20H29N3O3S
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| Canonical SMILES |
CCN1CCC(CC1)S(=O)(=O)NC(=O)NC2=C3CCCC3=CC4=C2CCC4
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| InChI |
InChI=1S/C20H29N3O3S/c1-2-23-11-9-16(10-12-23)27(25,26)22-20(24)21-19-17-7-3-5-14(17)13-15-6-4-8-18(15)19/h13,16H,2-12H2,1H3,(H2,21,22,24)
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| InChIKey |
OHIFQOUPTWBQLE-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Caterpiller protein 1.1 (NLRP3) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of Roche | |||
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