Drug Information
Drug General Information | Top | |||
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Drug ID |
DCZ16N
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Drug Name |
SD1002
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Drug Type |
Small molecular drug
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Indication | Alzheimer disease [ICD-11: 8A20; ICD-10: G30, G30.9; ICD-9: 331] | Preclinical | [1] |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Cathepsin B (CTSB) | Target Info | Inhibitor | [1] |
Cathepsin L (CTSL) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Lysosome | |||
Phagosome | ||||
Antigen processing and presentation | ||||
Proteoglycans in cancer | ||||
Rheumatoid arthritis | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
TGF_beta_Receptor Signaling Pathway | ||||
TCR Signaling Pathway | ||||
IL2 Signaling Pathway | ||||
Reactome | Endosomal/Vacuolar pathway | |||
Collagen degradation | ||||
Degradation of the extracellular matrix | ||||
Trafficking and processing of endosomal TLR | ||||
Assembly of collagen fibrils and other multimeric structures | ||||
MHC class II antigen presentation | ||||
WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS |
References | Top | |||
---|---|---|---|---|
REF 1 | Lysosomes as a therapeutic target. Nat Rev Drug Discov. 2019 Dec;18(12):923-948. |
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