miRNA General Information
miRNA Mature ID hsa-miR-155-3p
miRNA Stemloop AC MI0000681
miRNA Stemloop ID hsa-mir-155
Sequence cuccuacauauuagcauuaaca
TTD Target(s) Regulated by This miRNA Erbb2 tyrosine kinase receptor (HER2) Successful Target Target Info [1]
Interleukin-17 (IL17) Successful Target Target Info [2]
NAD-dependent deacetylase sirtuin-1 (SIRT1) Clinical trial Target Target Info [3]
Cellular tumor antigen p53 (TP53) Clinical trial Target Target Info [4]
Phosphatase and tensin homolog (PTEN) Literature-reported Target Target Info [5]
IL-1 receptor-associated kinase 3 (IRAK3) Literature-reported Target Target Info [6]
F-box and WD-40 domain protein 7 (Fbxw7) Literature-reported Target Target Info [7]
Protein(s) Regulated by This miRNA CREB3 regulatory factor Regulated Protein [8]
Interleukin-3 Regulated Protein [9]
REF 1 miR-155 downregulates ErbB2 and suppresses ErbB2-induced malignant transformation of breast epithelial cells. Oncogene. 2016 Nov 17;35(46):6015-6025.
REF 2 MicroRNA-155 regulates host immune response to postviral bacterial pneumonia via IL-23/IL-17 pathway. Am J Physiol Lung Cell Mol Physiol. 2016 Mar 1;310(5):L465-75.
REF 3 miR-124a and miR-155 enhance differentiation of regulatory T cells in patients with neuropathic pain. J Neuroinflammation. 2016 Sep 20;13(1):248.
REF 4 Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers. Clin Cancer Res. 2017 Jun 1;23(11):2891-2904.
REF 5 miR-155* mediates suppressive effect of PTEN 3'-untranslated region on AP-1/NF-B pathway in HTR-8/SVneo cells. Placenta. 2013 Aug;34(8):650-6.
REF 6 miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells. Blood. 2010 Dec 23;116(26):5885-94.
REF 7 MicroRNA-155-3p promotes hepatocellular carcinoma formation by suppressing FBXW7 expression. J Exp Clin Cancer Res. 2016 Jun 16;35(1):93.
REF 8 A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway.Autophagy. 2016 Jul 2;12(7):1129-52.
REF 9 miR-155 as a potential target of IL-3 signaling in primary AML cells.Leuk Res. 2017 Jun;57:57-59.

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