miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-384 | ||||
miRNA Stemloop AC | MI0001145 | ||||
miRNA Stemloop ID | hsa-mir-384 | ||||
Sequence | auuccuagaaauuguucaua | ||||
TTD Target(s) Regulated by This miRNA | NT-3 growth factor receptor (TrkC) | Successful Target | Target Info | [1] | |
Endoplasmic reticulum chaperone BiP (HSPA5) | Clinical trial Target | Target Info | [2] | ||
F-box and WD-40 domain protein 7 (Fbxw7) | Literature-reported Target | Target Info | [3] | ||
Insulin receptor substrate-1 (IRS1) | Clinical trial Target | Target Info | [4] | ||
References | |||||
REF 1 | Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. Hum Mutat. 2009 Jul;30(7):1062-71. | ||||
REF 2 | Downregulation of miR-384-5p attenuates rotenone-induced neurotoxicity in dopaminergic SH-SY5Y cells through inhibiting endoplasmic reticulum stress. Am J Physiol Cell Physiol. 2016 May 1;310(9):C755-63. | ||||
REF 3 | MiR-384 inhibits human colorectal cancer metastasis by targeting KRAS and CDC42. Oncotarget. 2016 Dec 20;7(51):84826-84838. | ||||
REF 4 | MiR-384 regulated IRS1 expression and suppressed cell proliferation of human hepatocellular carcinoma. Tumour Biol. 2016 Oct;37(10):14165-14171. |
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