miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-491-3p | ||||
miRNA Stemloop AC | MI0003126 | ||||
miRNA Stemloop ID | hsa-mir-491 | ||||
Sequence | cuuaugcaagauucccuucuac | ||||
TTD Target(s) Regulated by This miRNA | Cyclin-dependent kinase 6 (CDK6) | Successful Target | Target Info | [1] | |
Multidrug resistance protein 1 (ABCB1) | Clinical trial Target | Target Info | [2] | ||
Insulin-like growth factor-binding protein 2 (IGFBP2) | Literature-reported Target | Target Info | [3] | ||
References | |||||
REF 1 | Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell. 2010 Apr 2;141(1):129-41. | ||||
REF 2 | Atorvastatin attenuation of ABCB1 expression is mediated by microRNA miR-491-3p in Caco-2 cells. Eur J Pharm Sci. 2016 Oct 10;93:431-6. | ||||
REF 3 | Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma. Oncogene. 2015 Mar 26;34(13):1619-1628. |
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