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| Protein General Information (TTD Target) |
Top |
| Full Name |
Interleukin 4 receptor alpha (IL4R)
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Successful
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Target Info
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| UniProt ID |
IL4RA_HUMAN
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| Gene Name |
IL4R
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| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Janus kinase 1 (JAK-1) |
Target Info
|
PPI Info
|
[1] |
| Interacting Patented-recorded Target(s) |
Protein-tyrosine phosphatase SHP-1 (PTPN6) |
Target Info
|
PPI Info
|
[2] |
| References |
Top |
| REF 1 |
Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13003-8.
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| REF 2 |
The TORC1-activated Proteins, p70S6K and GRB10, Regulate IL-4 Signaling and M2 Macrophage Polarization by Modulating Phosphorylation of Insulin Rec... J Biol Chem. 2016 Nov 25;291(48):24922-24930.
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