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| Protein General Information (TTD Target) |
Top |
| Full Name |
Integrin beta-3 (ITGB3)
|
Literature-reported
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Target Info
|
| UniProt ID |
ITB3_HUMAN
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| Gene Name |
ITGB3
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| Gene ID |
3690
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| References |
Top |
| REF 1 |
Thrombspondin acts via integrin-associated protein to activate the platelet integrin alphaIIbbeta3. J Biol Chem. 1997 Jun 6;272(23):14740-6.
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| REF 2 |
Divalent cations differentially regulate integrin alphaIIb cytoplasmic tail binding to beta3 and to calcium- and integrin-binding protein. J Biol Chem. 1999 Jun 11;274(24):17257-66.
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| REF 3 |
A Leu262Pro mutation in the integrin beta(3) subunit results in an alpha(IIb)-beta(3) complex that binds fibrin but not fibrinogen. Blood. 2000 Jul 1;96(1):161-9.
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