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Protein General Information (TTD Target) |
Top |
Full Name |
Galectin-3 (LGALS3)
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Clinical trial
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Target Info
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UniProt ID |
LEG3_HUMAN
|
Gene Name |
LGALS3
|
Gene ID |
3958
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Interacting TTD Target Information |
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Interacting Successful Target(s) |
Epidermal growth factor receptor (EGFR) |
Target Info
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PPI Info
|
[1] |
Interacting Literature-reported Target(s) |
Endothelin-converting enzyme 1 (ECE1) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
Knockdown of GnT-Va expression inhibits ligand-induced downregulation of the epidermal growth factor receptor and intracellular signaling by inhibiting receptor endocytosis. Glycobiology. 2009 May;19(5):547-59.
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REF 2 |
Characterization of LGALS3 (galectin-3) as a player in DNA damage response. Cancer Biol Ther. 2014 Jul;15(7):840-50.
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