Protein-Protein Interaction Details
Protein General Information | Top | ||||
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Full Name | DNA replication licensing factor MCM3 (MCM3) | ||||
UniProt ID | MCM3_HUMAN | ||||
Gene Name | MCM3 | ||||
Gene ID | 4172 |
Interacting TTD Target Information | Top | ||||
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Interacting Clinical trial Target(s) | CDC7-related kinase (CDC7) | Target Info | PPI Info | [1] | |
Facilitates chromatin transcription complex (FACT) | Target Info | PPI Info | [2] | ||
Interacting Literature-reported Target(s) | DNA replication licensing factor MCM6 (MCM6) | Target Info | PPI Info | [3] | |
DNA replication licensing factor MCM7 (MCM7) | Target Info | PPI Info | [4] |
References | Top | ||||
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REF 1 | Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7. EMBO J. 1997 Jul 16;16(14):4340-51. | ||||
REF 2 | A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability. Mol Cell. 2010 Nov 24;40(4):645-57. | ||||
REF 3 | A high-throughput approach for measuring temporal changes in the interactome. Nat Methods. 2012 Sep;9(9):907-9. | ||||
REF 4 | Cell cycle regulation of human CDC6 protein. Intracellular localization, interaction with the human mcm complex, and CDC2 kinase-mediated hyperphosphorylation. J Biol Chem. 1999 Sep 3;274(36):25927-32. |
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