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Protein General Information |
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Full Name |
Mediator of RNA polymerase II transcription subunit 17 (MED17)
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UniProt ID |
MED17_HUMAN
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Gene Name |
MED17
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Gene ID |
9440
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Interacting TTD Target Information |
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Interacting Successful Target(s) |
Estrogen receptor beta (ESR2) |
Target Info
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PPI Info
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[1] |
Interacting Clinical trial Target(s) |
Cyclin-dependent kinase 8 (CDK8) |
Target Info
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PPI Info
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[2] |
Interacting Literature-reported Target(s) |
Sterol regulatory element binding protein-1 (SREBF1) |
Target Info
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PPI Info
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[3] |
References |
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REF 1 |
A large set of estrogen receptor -interacting proteins identified by tandem affinity purification in hormone-responsive human breast cancer cell nuclei. Proteomics. 2011 Jan;11(1):159-65.
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REF 2 |
Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. Mol Cell. 1999 Mar;3(3):361-70.
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REF 3 |
Structure, function, and activator-induced conformations of the CRSP coactivator. Science. 2002 Feb 8;295(5557):1058-62.
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