Protein-Protein Interaction Details
| Protein General Information (TTD Target) | Top | ||||
|---|---|---|---|---|---|
| Full Name | ERK activator kinase 7 (MAP2K7) | Literature-reported | Target Info | ||
| UniProt ID | MP2K7_HUMAN | ||||
| Gene Name | MAP2K7 | ||||
| Gene ID | 5609 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Clinical trial Target(s) | Stress-activated protein kinase JNK1 (JNK1) | Target Info | PPI Info | [1] | |
| MAPK/ERK kinase kinase 2 (MAP3K2) | Target Info | PPI Info | [2] | ||
| Leucine-rich repeat kinase 2 (LRRK2) | Target Info | PPI Info | [3] | ||
| Interacting Patented-recorded Target(s) | JNK-interacting protein 1 peptide (pepJIP1) | Target Info | PPI Info | [4] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7337-42. | ||||
| REF 2 | Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation. Mol Cell Biol. 2000 Apr;20(7):2334-42. | ||||
| REF 3 | MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2. J Neurochem. 2010 Mar;112(6):1593-604. | ||||
| REF 4 | Vaccinia virus B1R kinase interacts with JIP1 and modulates c-Jun-dependent signaling. J Virol. 2006 Aug;80(15):7667-75. | ||||
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