Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T01003 | Target Info | |||
| Target Name | Endoplasmic reticulum to nucleus signaling 1 (ERN1) | ||||
| Synonyms |
Serine/threonine-protein kinase/endoribonuclease IRE1; Ire1-alpha; IRE1a; IRE1; Inositol-requiring protein 1; hIRE1p; Endoplasmic reticulum-to-nucleus signaling 1
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|
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| Target Type | Clinical trial Target | ||||
| Gene Name | ERN1 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 144 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N-[5-(6,7-Dimethoxyquinolin-4-yl)oxypyridin-2-yl]-1-methyl-3-oxo-2,5-diphenylpyrazole-4-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3407848; BDBM50072073
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|
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
6-(5-Formyl-6-hydroxynaphthalen-2-yl)-N-propan-2-ylpyridine-2-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665054; SCHEMBL12674888; BDBM111370; US8614253, 32-6
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
6-(3-Fluoro-4-methylphenyl)-2-hydroxynaphthalene-1-carbaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665038; SCHEMBL12767141; BDBM111353; US8614253, 29-13
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
4-Bromo-2-[2-[2-[(5-bromo-2-hydroxy-3-methoxyphenyl)methylideneamino]ethyldisulfanyl]ethyliminomethyl]-6-methoxyphenol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665077; SCHEMBL12768067; BDBM111400; US8614253, 38-1
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-nitro-5-thiophen-3-ylbenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660405; SCHEMBL12767015; BDBM111253; US8614253, 43-13
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
Methyl 3-(3-fluoro-5-formyl-4-hydroxyphenyl)benzoate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660450; SCHEMBL12767056; BDBM111298; US8614253, 43-58
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
4-Bromo-2-methoxy-6-[(4-methoxyphenyl)methyliminomethyl]phenol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665078; SCHEMBL12768074; BDBM111401; US8614253, 38-2
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
2-Amino-N-[4-Methoxy-3-(Trifluoromethyl)phenyl]-4-Methyl-3-[2-(Methylamino)quinazolin-6-Yl]benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3407847; BDBM50072074; Q27454268; 3Z1
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
2-[2-[2-[(2-Hydroxy-3-methoxy-5-thiophen-2-ylphenyl)methylideneamino]ethyldisulfanyl]ethyliminomethyl]-6-methoxy-4-thiophen-2-ylphenol
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|
Investigative | Compound Info | ||
| Synonyms |
US8614253, 42-15; CHEMBL3665080; SCHEMBL12767222; BDBM111403; US8614253, 38-4
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
N-Benzyl-3-(5-formyl-6-hydroxynaphthalen-2-yl)-N-methylbenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665052; SCHEMBL12767161; BDBM111367; US8614253, 32-3
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-methoxy-5-(5-methylthiophen-2-yl)benzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660379; SCHEMBL12767009; BDBM111220; US8614253, 26-7
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
N-{5-[(6,7-Dimethoxyquinolin-4-Yl)oxy]pyridin-2-Yl}-1-Methyl-3-Oxo-2-Phenyl-5-(Pyridin-4-Yl)-2,3-Dihydro-1h-Pyrazole-4-Carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3407864; SCHEMBL200731; BDBM50072076; Q27454269
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|
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
2-Hydroxy-5-isoquinolin-4-yl-3-methoxybenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660386; SCHEMBL12767004; BDBM111227; US8614253, 26-14
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
5-(1,3-Dimethyl-2,4-dioxopyrimidin-5-yl)-2-hydroxy-3-methoxybenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
US8614253, 42-18; SCHEMBL1527140; CHEMBL3665101; BDBM111424; US8614253, 41-3
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
C1=CC(OC)=CC=C1CN=CC1=CC(C=2SC=CC=2)=CC(OC)=C1O
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|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL1527063; CHEMBL3665082; SCHEMBL12767223; BDBM111405; US8614253, 38-6
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
4-Bromo-2-(cyclopropyliminomethyl)-6-methoxyphenol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665079; SCHEMBL12768085; BDBM111402; US8614253, 38-3
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-5-[3-(piperidine-1-carbonyl)phenyl]benzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660471; SCHEMBL12767890; BDBM111319; US8614253, 43-79
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-6-(6-morpholin-4-ylpyridin-3-yl)naphthalene-1-carbaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665046; SCHEMBL12767152; BDBM111361; US8614253, 29-21
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-6-[3-(piperidine-1-carbonyl)phenyl]naphthalene-1-carbaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665050; SCHEMBL12767160; BDBM111365; US8614253, 32-1
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
4-[3-(N,N-Dimethylaminocarbonyl)phenyl]-2-formylphenol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660453; SCHEMBL12767059; DTXSID90685289; BDBM111301; MFCD11870971; ZINC65342048; US8614253, 43-61; 3'-Formyl-4'-hydroxy-N,N-dimethyl[1,1'-biphenyl]-3-carboxamide
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
3-Fluoro-2-hydroxy-5-isoquinolin-4-ylbenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660394; SCHEMBL12767001; BDBM111235; US8614253, 26-22
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-5-isoquinolin-4-yl-3-(trifluoromethyl)benzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660396; SCHEMBL12767013; BDBM111237; US8614253, 26-24
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-6-[3-(4-methylpiperazine-1-carbonyl)phenyl]naphthalene-1-carbaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665051; SCHEMBL12767165; BDBM111366; US8614253, 32-2
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
5-(1-Benzothiophen-3-yl)-3-fluoro-2-hydroxybenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660427; SCHEMBL12767820; BDBM111275; US8614253, 43-35
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
4-(3-Aminocarbonylphenyl)-2-formylphenol
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|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL2556984; CHEMBL3660452; DTXSID90685148; BDBM111300; MFCD11870958; ZINC65341879; US8614253, 43-60; 3'-Formyl-4'-hydroxy[1,1'-biphenyl]-3-carboxamide
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
5-(1-Benzothiophen-2-yl)-2-hydroxy-3-methoxybenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660406; SCHEMBL12767016; BDBM111254; US8614253, 43-14
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
3-Hydroxy-2-methylquinoline-4-carbaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL1527108; CHEMBL3665104; BDBM111436; US8614253, 42-11
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
2-(Cyclopropyliminomethyl)-6-methoxy-4-thiophen-2-ylphenol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665081; SCHEMBL12767224; BDBM111404; US8614253, 38-5
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
4-(Furan-2-yl)-2-[2-[2-[(2-hydroxy-3-methoxy-5-thiophen-2-ylphenyl)methylideneamino]ethyldisulfanyl]ethyliminomethyl]-6-methoxyphenol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3939769; SCHEMBL13018693; BDBM202543; US9241942, 38-4
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|
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| Activity |
EC50 = 50000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-5-[3-(morpholine-4-carbonyl)phenyl]benzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660470; SCHEMBL12767878; BDBM111318; US8614253, 43-78
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|
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
C1=CC2=C(C=O)C(O)=CC=C2C=C1C(N=1)=CC=CC=1C(=O)Nccn1ccocc1
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|
Investigative | Compound Info | ||
| Synonyms |
US8614253, 42-6; SCHEMBL1527057; CHEMBL3665057; BDBM111373; US8614253, 32-9
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|
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-6-[4-(morpholine-4-carbonyl)phenyl]naphthalene-1-carbaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665056; SCHEMBL12767178; BDBM111372; US8614253, 32-8
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|
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
3-(3-Fluoro-5-formyl-4-hydroxyphenyl)-N,N-dimethylbenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660467; SCHEMBL12767072; BDBM111315; US8614253, 43-75
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|
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
Methyl 4-(3-formyl-4-hydroxy-5-nitrophenyl)benzoate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660455; SCHEMBL12767064; SCHEMBL13018244; BDBM111303; US8614253, 43-63
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|
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-6-[6-(morpholine-4-carbonyl)pyridin-2-yl]naphthalene-1-carbaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665055; SCHEMBL12767158; BDBM111371; US8614253, 32-7
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|
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-methoxy-5-pyridin-2-ylbenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665099; SCHEMBL12767109; BDBM111422; US8614253, 41-1
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|
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
4-(3-Fluoro-5-formyl-4-hydroxyphenyl)benzoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660465; SCHEMBL12767069; BDBM111313; US8614253, 43-73
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|
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
3-(3-Fluoro-5-formyl-4-hydroxyphenyl)benzoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660451; SCHEMBL12767057; BDBM111299; US8614253, 43-59
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|
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-6-[6-(4-methylpiperazine-1-carbonyl)pyridin-2-yl]naphthalene-1-carbaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665058; SCHEMBL12767164; BDBM111374; US8614253, 32-10
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|
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-6-[5-(morpholine-4-carbonyl)furan-2-yl]naphthalene-1-carbaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3895174; SCHEMBL15592524; BDBM202539; US9241942, 32-11
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
4-Quinolinecarboxaldehyde, 3-hydroxy-
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Investigative | Compound Info | ||
| Synonyms |
US8614253, 42-9; SCHEMBL1527643; CHEMBL3665063; 3-hydroxyquinoline-4-carbaldehyde; BDBM111383; 3-hydroxy-quinoline-4-carbaldehyde; 3-Hydroxyquinoline-4-carboxaldehyde; DB-112609; US8614253, 34-2
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|
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
4-[4-(N,N-Dimethylaminocarbonyl)phenyl]-2-formylphenol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660469; SCHEMBL12767074; DTXSID20685292; BDBM111317; MFCD11870983; ZINC65342053; K-0634; US8614253, 43-77; 3'-Formyl-4'-hydroxy-N,N-dimethyl[1,1'-biphenyl]-4-carboxamide
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
4-(3-Fluoro-5-formyl-4-hydroxyphenyl)benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660466; SCHEMBL12767870; BDBM111314; US8614253, 43-74
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| Activity |
EC50 = 60000 nM
|
[2] | |||
| Compound Name |
3-Fluoro-2-hydroxy-5-thiophen-2-ylbenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
US8614253, 43-10; CHEMBL3660310; SCHEMBL12766756; BDBM110972; US8614253, .3-3
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
5-(1-Benzothiophen-3-yl)-2-hydroxy-3-methoxybenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660407; SCHEMBL12767017; BDBM111255; US8614253, 43-15
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|
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-nitro-5-thiophen-2-ylbenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660309; SCHEMBL12766743; BDBM110971; BDBM111251; US8614253, .3-2; US8614253, 43-11
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|
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-5-thiophen-2-yl-3-(trifluoromethyl)benzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660425; SCHEMBL12767025; BDBM111273; US8614253, 43-33
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|
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-methoxy-5-(2-pyridin-3-ylethynyl)benzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL1527100; CHEMBL3665105; BDBM111439; US8614253, 42-14
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|
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-methoxy-5-quinolin-5-ylbenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660383; SCHEMBL12767000; BDBM111224; US8614253, 26-11
Click to Show/Hide
|
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-nitro-5-quinolin-5-ylbenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660385; SCHEMBL12767005; BDBM111226; US8614253, 26-13
Click to Show/Hide
|
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
2-Methoxy-6-[(E)-5H-tetrazol-5-yliminomethyl]-4-thiophen-2-ylphenol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3934961; SCHEMBL12767232; BDBM202545; US9241942, 38-11
Click to Show/Hide
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-5-(3-thienyl)benzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
2-FORMYL-4-(THIOPHEN-3-YL)PHENOL; 2-Hydroxy-5-(thiophen-3-yl)benzaldehyde; 2-Hydroxy-5-(thien-3-yl)benzaldehyde; SCHEMBL6639987; CHEMBL3660409; DTXSID00602407; BDBM111257; MFCD06802126; ZINC16946468; 2-hydroxy-5-thiophen-3-ylbenzaldehyde; AKOS004116227; BB 0223174; K-7195; US8614253, 43-17
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|
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-methoxy-5-pyridin-4-ylbenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
US8614253, 26-1; CHEMBL3660336; SCHEMBL12766785; BDBM110999; US8614253, .3-30
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|
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
3-Hydroxy-4-(piperidin-1-ylmethyl)naphthalene-2-carbaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665095; SCHEMBL12767744; BDBM111418; US8614253, 39-2
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|
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
3'-Formyl-4'-hydroxy-5'-methoxybiphenyl-3-carboxylic acid
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|
Investigative | Compound Info | ||
| Synonyms |
US8614253, 42-1; US8614253, 43-1; SCHEMBL1527101; CHEMBL3660316; BDBM110979; 3-(3-formyl-4-hydroxy-5-methoxyphenyl)benzoic acid; A1-13618; US8614253, .3-10
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-5-(6-methoxypyridin-3-yl)-3-nitrobenzaldehyde
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660382; SCHEMBL12767003; BDBM111223; US8614253, 26-10
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|
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| Activity |
EC50 = 70000 nM
|
[2] | |||
| Compound Name |
4-Bromo-2-methoxy-6-[(E)-5H-tetrazol-5-yliminomethyl]phenol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3910582; SCHEMBL12768103; BDBM202544; US9241942, 38-10
Click to Show/Hide
|
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| Activity |
EC50 = 75000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-5-[3-(morpholine-4-carbonyl)phenyl]-3-nitrobenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660436; SCHEMBL12767827; BDBM111284; US8614253, 43-44
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-nitro-5-pyrimidin-5-ylbenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660402; SCHEMBL12766877; BDBM111248; US8614253, 43-8
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
5-(1-Benzofuran-2-yl)-2-hydroxy-3-methoxybenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660389; SCHEMBL12767010; BDBM111230; US8614253, 26-17
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-(3-Fluoro-5-formyl-4-hydroxyphenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660434; SCHEMBL12767044; BDBM111282; US8614253, 43-42
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
Methyl 3-(3-formyl-4-hydroxy-5-nitrophenyl)benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660444; SCHEMBL12767839; BDBM111292; US8614253, 43-52
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-(3-Formyl-4-hydroxy-5-methoxyphenyl)-N,N-dimethylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660429; SCHEMBL12767037; BDBM111277; US8614253, 43-37
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-Fluoro-2-hydroxy-5-pyrimidin-5-ylbenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
US8614253, 43-81; CHEMBL3660311; SCHEMBL12766771; BDBM110973; US8614253, .3-4
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-(2-Hydroxyethyliminomethyl)-4-bromo-6-methoxyphenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665088; SCHEMBL12768108; BDBM111411; US8614253, 38-12
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
5-(1-Benzothiophen-2-yl)-3-fluoro-2-hydroxybenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660424; SCHEMBL12767026; BDBM111272; US8614253, 43-32
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
5-(Furan-2-yl)-2-hydroxybenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-(2-Furyl)-2-hydroxybenzaldehyde; CHEMBL3660463; SCHEMBL12767867; DTXSID30602435; BDBM111311; ZINC16946793; AKOS004116576; BB 0223287; US8614253, 43-71
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
4-Bromo-2-hydroxy-3-(1,3-thiazolidin-2-yl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665071; SCHEMBL12767256; BDBM111391; US8614253, 36-5
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 80000 nM
|
[2] | |||
| Compound Name |
4-(3-Fluoro-5-formyl-4-hydroxyphenyl)-N,N-dimethylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660473; SCHEMBL12767083; BDBM111322; US8614253, 43-82
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-Fluoro-2-hydroxy-5-[4-(morpholine-4-carbonyl)phenyl]benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665100; SCHEMBL12768143; BDBM111423; US8614253, 41-2
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 80000 nM
|
[2] | |||
| Compound Name |
4-(3-Formyl-4-hydroxy-5-nitrophenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660457; SCHEMBL12767857; BDBM111305; US8614253, 43-65
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
Ethyl 2-(3-formyl-4-hydroxy-5-methoxyphenyl)benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660442; SCHEMBL12767052; BDBM111290; US8614253, 43-50
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
5-(2,3-Dihydro-1-benzofuran-5-yl)-2-hydroxy-3-methoxybenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
US8614253, 43-2; CHEMBL3660330; SCHEMBL12766779; BDBM110993; US8614253, .3-24
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
Benzaldehyde, 3-fluoro-5-(3-furanyl)-2-hydroxy-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660423; SCHEMBL12767029; BDBM111271; US8614253, 43-31
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-5-pyridin-3-yl-3-(trifluoromethyl)benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660392; SCHEMBL12766991; BDBM111233; US8614253, 26-20
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
Benzaldehyde, 5-(3-furanyl)-2-hydroxy-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660417; SCHEMBL12767813; BDBM111265; ZINC96312904; US8614253, 43-25
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
Benzaldehyde, 5-(3-furanyl)-2-hydroxy-3-methoxy-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660418; SCHEMBL12767028; BDBM111266; US8614253, 43-26
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-5-[4-(morpholine-4-carbonyl)phenyl]-3-(trifluoromethyl)benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660439; SCHEMBL12767832; BDBM111287; US8614253, 43-47
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
5-(3,5-Dimethyl-1,2-oxazol-4-yl)-2-hydroxybenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660410; SCHEMBL12767795; DTXSID60685039; BDBM111258; US8614253, 43-18
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-[3-Formyl-4-hydroxy-5-(trifluoromethyl)phenyl]-N,N-dimethylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660441; SCHEMBL12767049; BDBM111289; US8614253, 43-49
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-5-isoquinolin-4-yl-3-nitrobenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660395; SCHEMBL12767006; BDBM111236; US8614253, 26-23
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-Fluoro-2-hydroxy-5-pyridin-3-ylbenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660377; SCHEMBL12766990; BDBM111218; US8614253, 26-5
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-(3-Formyl-4-hydroxy-5-methoxyphenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL3507214; CHEMBL3660432; BDBM111280; US8614253, 43-40
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-Formyl-2-hydroxy-4-pyrimidin-5-ylbenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660375; SCHEMBL12767752; BDBM111216; US8614253, 26-3
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
5-(1-Benzothiophen-3-yl)-2-hydroxybenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660416; SCHEMBL12767810; BDBM111264; US8614253, 43-24
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
Ethyl 5-(5-formyl-6-hydroxynaphthalen-2-yl)thiophene-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
US8614253, 42-7; US8614253, 32-13; CHEMBL3665048; SCHEMBL12767154; BDBM111363; US8614253, 31-1
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-Fluoro-5-(furan-2-yl)-2-hydroxybenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660391; SCHEMBL12767014; BDBM111232; US8614253, 26-19
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
Methyl 4-(3-formyl-4-hydroxy-5-methoxyphenyl)benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660400; SCHEMBL12767776; BDBM111243; US8614253, 43-3
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
4-(3-Formyl-4-hydroxy-5-methoxyphenyl)-N,N-dimethylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660430; SCHEMBL12767038; BDBM111278; US8614253, 43-38
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
4-(3-Formyl-4-hydroxy-5-methoxyphenyl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660440; SCHEMBL12767050; BDBM111288; US8614253, 43-48
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
5-(3,5-Dimethyl-1,2-oxazol-4-yl)-3-fluoro-2-hydroxybenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660390; SCHEMBL12766987; BDBM111231; US8614253, 26-18
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-Fluoro-2-hydroxy-5-(1-methylpyrazol-4-yl)benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660398; SCHEMBL12767012; BDBM111239; US8614253, 26-26
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
Ethyl 2-(5-bromo-2-hydroxy-3-methoxyphenyl)-1,3-thiazolidine-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665068; SCHEMBL12767263; BDBM111388; US8614253, 36-2
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 80000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-methoxy-6-pyridin-4-ylbenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
US8614253, .3-74; US8614253, 43-83; CHEMBL3660368; SCHEMBL12766901; BDBM111036; US8614253, .3-67
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
Ethyl 2-(2-hydroxy-3-methoxy-5-thiophen-2-ylphenyl)-1,3-thiazolidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
US8614253, 42-13; SCHEMBL1527078; CHEMBL3665070; BDBM111390; US8614253, 36-4
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 80000 nM
|
[2] | |||
| Compound Name |
5-(2,3-Dihydro-1-benzofuran-5-yl)-2-hydroxybenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660412; SCHEMBL12767802; BDBM111260; ZINC96312854; US8614253, 43-20
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-methoxy-5-(4-methylsulfonylphenyl)benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660433; SCHEMBL12767041; BDBM111281; US8614253, 43-41
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
5-(5-Acetylthiophen-2-yl)-3-fluoro-2-hydroxybenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660393; SCHEMBL12766993; BDBM111234; US8614253, 26-21
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-Methoxy-6-(1,3-thiazolidin-2-yl)-4-thiophen-2-ylphenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665074; SCHEMBL12767262; BDBM111394; US8614253, 36-8
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 80000 nM
|
[2] | |||
| Compound Name |
2-(2,3-Dibromo-5-ethoxy-6-hydroxyphenyl)-1,3-thiazolidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665076; SCHEMBL12767730; BDBM111396; US8614253, 36-10
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 80000 nM
|
[2] | |||
| Compound Name |
5-(1-Benzothiophen-2-yl)-2-hydroxy-3-nitrobenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660422; SCHEMBL12767818; BDBM111270; US8614253, 43-30
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
4-(3-Formyl-4-hydroxy-5-nitrophenyl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660459; SCHEMBL12767065; SCHEMBL13018245; BDBM111307; US8614253, 43-67
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
5-(2,4-Dimethyl-1H-pyrrol-3-yl)-2-hydroxy-3-nitrobenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4113732; BDBM202538; US9241942, 27-19
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
5-(3,5-Dimethyl-1,2-oxazol-4-yl)-2-hydroxy-3-methoxybenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660403; SCHEMBL12767020; BDBM111249; US8614253, 43-9
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-5-(pyridin-3-yl)benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL6644954; CHEMBL3660426; BDBM111274; ZINC39619835; 2-hydroxy-5-pyridin-3-ylbenzaldehyde; BP-11717; Benzaldehyde, 2-hydroxy-5-(3-pyridinyl)-; US8614253, 43-34
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-(3-Formyl-4-hydroxy-5-nitrophenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660456; SCHEMBL12767854; BDBM111304; US8614253, 43-64
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-(3-Formyl-4-hydroxy-5-methoxyphenyl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660445; SCHEMBL12767837; BDBM111293; US8614253, 43-53
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-(5-Bromo-2-hydroxy-3-methoxyphenyl)-1,3-thiazolidine-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665067; SCHEMBL12768030; BDBM111387; US8614253, 36-1
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 80000 nM
|
[2] | |||
| Compound Name |
3-Fluoro-2-hydroxy-5-(6-methoxypyridin-3-yl)benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660380; SCHEMBL12766985; BDBM111221; US8614253, 26-8
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-(6-Bromo-3-carboxy-2-hydroxyphenyl)-1,3-thiazolidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665072; SCHEMBL12767265; BDBM111392; US8614253, 36-6
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 80000 nM
|
[2] | |||
| Compound Name |
6-(4-Chloro-3-methylphenyl)-2-hydroxynaphthalene-1-carbaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665039; SCHEMBL12767142; BDBM111354; US8614253, 29-14
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 80000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-methoxy-6-pyrimidin-5-ylbenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660462; SCHEMBL12767066; BDBM111310; US8614253, 43-70
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
Benzaldehyde, 5-(3-furanyl)-2-hydroxy-3-nitro-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660421; SCHEMBL12767027; BDBM111269; US8614253, 43-29
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-Fluoro-2-hydroxy-5-thiophen-3-ylbenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660414; SCHEMBL12767033; BDBM111262; US8614253, 43-22
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-3-methoxy-5-(1H-pyrazol-4-yl)benzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660397; SCHEMBL12767011; BDBM111238; US8614253, 26-25
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
3-(3-Formyl-4-hydroxy-5-nitrophenyl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660454; SCHEMBL12767063; SCHEMBL13018249; BDBM111302; US8614253, 43-62
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
2-Hydroxy-5-(4-methylsulfonylphenyl)-3-nitrobenzaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660437; SCHEMBL12767829; BDBM111285; US8614253, 43-45
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
4-Bromo-2-methoxy-6-(1,3-thiazolidin-2-yl)phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665069; SCHEMBL12767273; BDBM111389; US8614253, 36-3
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 80000 nM
|
[2] | |||
| Compound Name |
4-Bromo-2-methoxy-6-[(E)-1,3-thiazol-2-yliminomethyl]phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665089; SCHEMBL12768111; BDBM111412; US8614253, 38-13
Click to Show/Hide
|
||||
| Activity |
EC50 = 80000 nM
|
[2] | |||
| Compound Name |
Methyl 4-(3-fluoro-5-formyl-4-hydroxyphenyl)benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660449; SCHEMBL12767054; BDBM111297; US8614253, 43-57
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
6-(3-Chloro-4-methylphenyl)-2-hydroxynaphthalene-1-carbaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665040; SCHEMBL12767143; BDBM111355; US8614253, 29-15
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| Activity |
EC50 ~ 80000 nM
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[2] | |||
| Compound Name |
3-Hydroxy-4-(morpholin-4-ylmethyl)naphthalene-2-carbaldehyde
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Investigative | Compound Info | ||
| Synonyms |
US8614253, 42-16; SCHEMBL1527117; CHEMBL3665094; BDBM111417; US8614253, 39-1
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
5-(1-Benzothiophen-3-yl)-2-hydroxy-3-nitrobenzaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660388; SCHEMBL12767008; BDBM111229; US8614253, 26-16
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
2-(2-Hydroxy-3-methoxy-5-thiophen-2-ylphenyl)-1,3-thiazolidine-4-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665075; SCHEMBL12767258; BDBM111395; US8614253, 36-9
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| Activity |
EC50 ~ 80000 nM
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[2] | |||
| Compound Name |
3'-Formyl-4'-hydroxy[1,1'-biphenyl]-3-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
4-(3-Carboxyphenyl)-2-formylphenol; SCHEMBL6638046; CHEMBL3660460; DTXSID20602404; BDBM111308; MFCD06802123; ZINC16946460; AKOS004116189; 3-(3-formyl-4-hydroxyphenyl)benzoic acid; BB 0223170; US8614253, 43-68
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
2-Hydroxy-5-(2-pyridin-2-ylethynyl)benzaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3920586; SCHEMBL12767112; BDBM202541; US9241942, 37-1
Click to Show/Hide
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| Activity |
EC50 ~ 80000 nM
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[2] | |||
| Compound Name |
4-(3-Formyl-4-hydroxy-5-nitrophenyl)-N,N-dimethylbenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660438; SCHEMBL12767831; BDBM111286; US8614253, 43-46
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
2-Hydroxy-3-methoxy-5-(2-thiophen-2-ylethynyl)benzaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3911792; SCHEMBL12767113; BDBM202542; US9241942, 37-3
Click to Show/Hide
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| Activity |
EC50 ~ 80000 nM
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[2] | |||
| Compound Name |
Ethyl 2-(2,3-dibromo-5-ethoxy-6-hydroxyphenyl)-1,3-thiazolidine-4-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665073; SCHEMBL12767267; BDBM111393; US8614253, 36-7
Click to Show/Hide
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| Activity |
EC50 ~ 80000 nM
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[2] | |||
| Compound Name |
2-Hydroxy-3-methoxy-5-[3-(morpholine-4-carbonyl)phenyl]benzaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660431; SCHEMBL12767042; BDBM111279; US8614253, 43-39
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
3-(3-Formyl-4-hydroxy-5-nitrophenyl)-N,N-dimethylbenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660458; SCHEMBL12767859; BDBM111306; US8614253, 43-66
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
2-Hydroxy-5-(1-methylpyrazol-4-yl)-3-nitrobenzaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660399; SCHEMBL12767778; BDBM111240; US8614253, 26-27
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
4-(3-Formyl-4-hydroxy-5-methoxyphenyl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660428; SCHEMBL12767036; BDBM111276; US8614253, 43-36
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
5-(2,3-Dihydro-1-benzofuran-5-yl)-3-fluoro-2-hydroxybenzaldehyde
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660413; SCHEMBL12767032; BDBM111261; US8614253, 43-21
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
4-[Benzo(B)thiophen-2-YL]-2-formylphenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660415; SCHEMBL12767811; BDBM111263; MFCD11871071; K-0635; US8614253, 43-23
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
Ethyl 5-(3-formyl-4-hydroxy-5-methoxyphenyl)thiophene-2-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660446; SCHEMBL12767053; BDBM111294; US8614253, 43-54
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
Methyl 3-(3-formyl-4-hydroxy-5-methoxyphenyl)benzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660443; SCHEMBL12767051; BDBM111291; US8614253, 43-51
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
5-(Furan-2-yl)-2-hydroxy-3-nitrobenzaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660420; SCHEMBL12767808; BDBM111268; US8614253, 43-28
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
2-Hydroxy-5-(pyridin-4-yl)benzaldehyde
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Investigative | Compound Info | ||
| Synonyms |
Benzaldehyde, 2-hydroxy-5-(4-pyridinyl)-; 6-oxo-3-(1H-pyridin-4-ylidene)cyclohexa-1,4-diene-1-carbaldehyde; SCHEMBL4734113; CHEMBL3660376; BDBM111217; ZINC96312828; 2-Hydroxy-5-(4-pyridinyl)benzaldehyde; 2-Hydroxy-5-pyridin-4-yl-benzaldehyde; DS-013398; US8614253, 26-4
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
5-(3-Formyl-4-hydroxy-5-methoxyphenyl)thiophene-2-carboxylic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660447; SCHEMBL12767711; BDBM111295; US8614253, 43-55
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
3-[3-Formyl-4-hydroxy-5-(trifluoromethyl)phenyl]benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660435; SCHEMBL12767045; BDBM111283; US8614253, 43-43
Click to Show/Hide
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| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
6-Hydroxy-4-methyl-2-oxo-1H-quinoline-5-carbaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3665066; SCHEMBL12767716; BDBM111386; US8614253, 35-2
Click to Show/Hide
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| Activity |
EC50 ~ 80000 nM
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[2] | |||
| Compound Name |
3-Fluoro-2-hydroxy-5-quinolin-5-ylbenzaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3660384; SCHEMBL12766999; BDBM111225; US8614253, 26-12
Click to Show/Hide
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||||
| Activity |
EC50 = 80000 nM
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[2] | |||
| Compound Name |
N-[4-[3-[2-(3-Methylbutylamino)pyrimidin-4-yl]pyridin-2-yl]oxynaphthalen-1-yl]-1H-benzimidazol-2-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3355994; BDBM50043775
Click to Show/Hide
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||||
| Activity |
IC50 ~ 99000 nM
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[3] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of 1H-pyrazol-3(2H)-ones as potent and selective inhibitors of protein kinase R-like endoplasmic reticulum kinase (PERK). J Med Chem. 2015 Feb 12;58(3):1426-41. | ||||
| REF 2 | US patent application no. 9241942B2, IRE-1alpha inhibitors | ||||
| REF 3 | Unfolded Protein Response in Cancer: IRE1alpha Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability. ACS Med Chem Lett. 2014 Sep 24;6(1):68-72. | ||||
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