Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T01851 | Target Info | |||
| Target Name | Integrin beta-1 (ITGB1) | ||||
| Synonyms |
VLA-4 subunit beta; MSK12; MDF2; Integrin VLA-4 beta subunit; Glycoprotein IIa; GPIIA; Fibronectin receptor subunit beta; Fibronectin receptor beta subunit; FNRB; CD29 antigen; CD29; Beta(1) integrin
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| Target Type | Clinical trial Target | ||||
| Gene Name | ITGB1 | ||||
| Biochemical Class | Integrin | ||||
| UniProt ID | |||||
| Non Binders of This Target (in total, 1 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(3S,6R,9S,12R,15S,20S,23R)-15-Amino-12-(3-amino-3-oxopropyl)-9-[(2S)-butan-2-yl]-6-(carboxymethyl)-3-(hydroxymethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosane-20-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL154655; BDBM50137079
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| Activity |
IC50 = 1443000 nM
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[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis and structure-activity relationship of mannose-based peptidomimetics selectively blocking integrin alpha4beta7 binding to mucosal addressin cell adhesion molecule-1. J Med Chem. 2003 Dec 18;46(26):5752-62. | ||||
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