Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T10965 | Target Info | |||
| Target Name | P-selectin (SELP) | ||||
| Synonyms |
SELP; PADGEM; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; Granule membrane protein 140; GMP-140; CD62P
Click to Show/Hide
|
||||
| Target Type | Successful Target | ||||
| Gene Name | SELP | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 37 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Bimosiamose
Click to Show/Hide
|
Phase 2a | Compound Info | ||
| Synonyms |
TBC 1269; TBC-1269
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[1] | |||
| Compound Name |
Galactocerebroside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL110111; BDBM50061123
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
3-{4-[5-{4-[2-(3-Phenyl-propylcarbamoyl)-vinyl]-phenyl}-2-(4-pyrrolidin-1-yl-phenyl)-1H-imidazol-4-yl]-phenyl}-4,5-dihydro-isoxazole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL305599; SCHEMBL7994331; BDBM50100512
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[3] | |||
| Compound Name |
(5-{2-[4-(3,4,5-Trihydroxy-phenyl)-butyrylamino]-phenyl}-thiophen-2-yl)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220208; BDBM50205390
Click to Show/Hide
|
||||
| Activity |
IC50 = 53900 nM
|
[4] | |||
| Compound Name |
2-[3-[2-[4-[(3,4,5-Trihydroxybenzoyl)amino]butanoylamino]phenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219991; BDBM50205379; {2''-[4-(3,4,5-trihydroxy-benzoylamino)-butyrylamino]-biphenyl-3-yl}-acetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 57200 nM
|
[4] | |||
| Compound Name |
(5R,9S,13S,14R)-5,9,13-Trimethyl-14-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}tetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecane-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215326; CHEMBL312246; BDBM50290267
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[5] | |||
| Compound Name |
(2R)-2-[(2S,3R,4S,5S,6R)-3,5-Dibenzoyloxy-2-[(2R,3R)-1,4-dioxo-1,4-di(propan-2-yloxy)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-6-(hydroxymethyl)oxan-4-yl]oxy-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3335530; BDBM50026881
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[6] | |||
| Compound Name |
2-[3-[5-[6-[3-[3-(Carboxymethyl)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]hexyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303881; BDBM50422287
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[7] | |||
| Compound Name |
2-(2-{{1-Phenethylcarbamoyl-3-[4-(4-phenoxy-phenoxy)-phenyl]-propyl}-[2-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yl)-acetyl]-amino}-acetylamino)-pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL307807; BDBM50071589
Click to Show/Hide
|
||||
| Activity |
IC50 = 76000 nM
|
[8] | |||
| Compound Name |
2-[(2,5-Dichlorophenyl)methylamino]-N-(1-methylpiperidin-4-yl)-4-(piperidin-4-ylamino)pyrimidine-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2312647; BDBM50425874
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 80000 nM
|
[9] | |||
| Compound Name |
(3S,4R)-4-[[2-(3,5-Dichloroanilino)-5-(4-fluorophenyl)pyrimidin-4-yl]amino]oxolan-3-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2312656; BDBM50425867
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 80000 nM
|
[9] | |||
| Compound Name |
2-{(1-Phenethylcarbamoyl-ethyl)-[2-(3,4,5-trihydroxy-6-phenoxymethyl-tetrahydro-pyran-2-yl)-acetyl]-amino}-pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL310195; BDBM50071593
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[8] | |||
| Compound Name |
2-{(1-Tert-Butylcarbamoyl-ethyl)-[2-(3,4,5-trihydroxy-6-phenoxymethyl-tetrahydro-pyran-2-yl)-acetyl]-amino}-pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL421697; BDBM50071592
Click to Show/Hide
|
||||
| Activity |
IC50 = 87000 nM
|
[8] | |||
| Compound Name |
4-[5-[4-[(E)-2-(Hexadecylcarbamoyl)vinyl]phenyl]-1H-imidazole-4-yl]cinnamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL293171; SCHEMBL8192149; SCHEMBL8192150; BDBM50100506; 3-(4-{5-[4-(2-Hexadecylcarbamoyl-vinyl)-phenyl]-1H-imidazol-4-yl}-phenyl)-acrylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 98000 nM
|
[3] | |||
| Compound Name |
4-[4-[4-(5-Carboxy-2-isoxazoline-3-yl)phenyl]-5-[4-[(E)-2-(3-phenylpropylcarbamoyl)vinyl]phenyl]-1H-imidazole-2-yl]cinnamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL292851; SCHEMBL7997348; BDBM50100511
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[3] | |||
| Compound Name |
Sodium; 3,5-dihydroxy-2-[5-hydroxy-2-hydroxymethyl-6-(2-tetradecyl-hexadecyloxy)-4-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yloxy]-6-hydroxymethyl-tetrahydro-pyran-4-sulfonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3085443; BDBM50050500
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[10] | |||
| Compound Name |
2-(Benzo[b]thiophen-3-ylmethyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218985; SCHEMBL2252455; BDBM50201966; 2-(1-benzothiophen-3-ylmethyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[11] | |||
| Compound Name |
3'-O-Sulfated sialyl Lewis x
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2029056
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[12] | |||
| Compound Name |
(2R)-2-[(2S,3R,4S,5S,6R)-3,5-Dibenzoyloxy-2-[(2R,3R)-1,4-dimethoxy-1,4-dioxo-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-6-(hydroxymethyl)oxan-4-yl]oxy-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3335528; BDBM50026870
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[6] | |||
| Compound Name |
2-{[1-(Methoxycarbonylmethyl-carbamoyl)-ethyl]-[2-(3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-acetyl]-amino}-pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77658; BDBM50071595
Click to Show/Hide
|
||||
| Activity |
IC50 = 118000 nM
|
[8] | |||
| Compound Name |
2-(2-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]-quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218473; SCHEMBL1291984; BDBM50201959; 2-[(2-chlorophenyl)methyl]-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 123000 nM
|
[11] | |||
| Compound Name |
2-(4-Chlorophenylamino)-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218629; BDBM50201978
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[11] | |||
| Compound Name |
2-{[1-(Methoxycarbonylmethyl-carbamoyl)-ethyl]-[2-(3,4,5-trihydroxy-6-{3-[4-(4-phenoxy-phenoxy)-phenyl]-propoxymethyl}-tetrahydro-pyran-2-yl)-acetyl]-amino}-pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306480; BDBM50071586
Click to Show/Hide
|
||||
| Activity |
IC50 = 127000 nM
|
[8] | |||
| Compound Name |
2-(3-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]-quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219921; SCHEMBL1292183; BDBM50201983; 2-[(3-chlorophenyl)methyl]-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 138000 nM
|
[11] | |||
| Compound Name |
2-[[1-(Methoxycarbonylmethyl-carbamoyl)-2-(3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-ethyl]-(3-methoxycarbonyl-propionyl)-amino]-pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL78221; BDBM50071591
Click to Show/Hide
|
||||
| Activity |
IC50 = 142000 nM
|
[8] | |||
| Compound Name |
2-(4-Chlorobenzyl)-8-(fur-3-yl)-3-hydroxyquinoline-4-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL373973; SCHEMBL4189707; BDBM50201967; 2-(4-chlorobenzyl)-8-(fur-3-yl)-3-hydroxyquinoline-4-carboxylicacid; 2-[(4-chlorophenyl)methyl]-8-(furan-3-yl)-3-hydroxyquinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[11] | |||
| Compound Name |
Chembl348516
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215429; BDBM50291308
Click to Show/Hide
|
||||
| Activity |
IC50 = 160000 nM
|
[13] | |||
| Compound Name |
2-(4-Chlorobenzyl)-3-(thiophene-2-carbonyloxy)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL376304; BDBM50201976
Click to Show/Hide
|
||||
| Activity |
IC50 = 175000 nM
|
[11] | |||
| Compound Name |
2-((5-Bromo-1H-indol-3-yl)methyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL385991; BDBM50201958
Click to Show/Hide
|
||||
| Activity |
IC50 = 175000 nM
|
[11] | |||
| Compound Name |
2-(4-Chlorobenzyl)-3-(cyclohexanecarbonyloxy)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218610; BDBM50201991
Click to Show/Hide
|
||||
| Activity |
IC50 = 175000 nM
|
[11] | |||
| Compound Name |
2-((5-Chloro-1H-indol-3-yl)methyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218362; BDBM50201973
Click to Show/Hide
|
||||
| Activity |
IC50 = 175000 nM
|
[11] | |||
| Compound Name |
3-Benzoyloxy-2-[(4-chlorophenyl)methyl]-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL217973; BDBM50201998; 3-(benzoyloxy)-2-(4-chlorobenzyl)-7,8,9,10-tetrahydrobenzo-[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 190000 nM
|
[11] | |||
| Compound Name |
(2R)-2-[(2S,3R,4S,5S,6R)-3-Benzoyloxy-2-[(2R,3R)-1,4-dioxo-1,4-di(propan-2-yloxy)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3335529; BDBM50026871
Click to Show/Hide
|
||||
| Activity |
IC50 = 190000 nM
|
[6] | |||
| Compound Name |
2-(4-Chloro-benzyl)-3-hydroxy-8-phenyl-quinoline-4-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL375117; SCHEMBL4180965; BDBM50201974; 2-(4-chlorobenzyl)-3-hydroxy-8-phenylquinoline-4-carboxylicacid; 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-phenylquinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[11] | |||
| Compound Name |
2-[3-[5-[[3,5-Bis[[3-[3-(carboxymethyl)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl]phenyl]methyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303876; BDBM50422288
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[7] | |||
| Compound Name |
3-Hydroxy-2-((5-methyl-1H-indol-3-yl)methyl)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218363; BDBM50201965
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[11] | |||
| Compound Name |
3-Hydroxy-2-(5-methylthiophen-2-yl)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218545; BDBM50201989
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[11] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 104 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
3-hydroxy-2-phenylquinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oxycinchophen; 485-89-2; Oxinofen; Chinoxone; Fenidrone; 3-hydroxy-2-phenylquinoline-4-carboxylic acid; Hydroxycinchophene; Sintofene; Magnofenyl; Reumartril; Magnophenyl; 3-Hydroxy-2-phenylcinchoninic acid; 3-Hydroxycinchophen; oxicinchophen; Oxicinchophenum; Oxycinchophen [INN:BAN]; Oxicincofeno [INN-Spanish]; UNII-UK6392GD5W; Oxycinchophene [INN-French]; Oxycinchophenum [INN-Latin]; 3-Hydroxy-2-phenyl-4-quinolinecarboxylic acid; 3-Hydroxy-2-phenyl-chinchoninsaeure; EINECS 207-624-4; NSC 41784; BRN 0224526; CHEMBL219376
Click to Show/Hide
|
||||
| Activity |
IC50 = 6500000 nM
|
[11] | |||
| Compound Name |
(5-{2-[(3',4',5'-Trihydroxy-biphenyl-2-carbonyl)-amino]-phenyl}-thiophen-2-yl)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL221273; SCHEMBL4665168; BDBM50205399; 2-[5-[2-[[2-(3,4,5-trihydroxyphenyl)benzoyl]amino]phenyl]thiophen-2-yl]acetic acid; (5-{2-[(3'',4'',5''-trihydroxy-biphenyl-2-carbonyl)-amino]-phenyl}-thiophen-2-yl)-acetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 212100 nM
|
[4] | |||
| Compound Name |
2-(4-Chlorobenzyl)-3-hydroxy-8-(thien-3-yl)quinoline-4-carboxylicacid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219430; SCHEMBL4187703; BDBM50201993; 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-thiophen-3-ylquinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 225000 nM
|
[11] | |||
| Compound Name |
2-[3-[5-[[3-[[3-[3-(Carboxymethyl)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl]phenyl]methyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303889; BDBM50422294
Click to Show/Hide
|
||||
| Activity |
IC50 = 225000 nM
|
[7] | |||
| Compound Name |
2-((1H-Indol-3-yl)methyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218986; SCHEMBL1292690; BDBM50201988; 3-hydroxy-2-(1H-indol-3-ylmethyl)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 225000 nM
|
[11] | |||
| Compound Name |
3-Hydroxy-2-(1H-indol-3-yl)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220198; BDBM50201995
Click to Show/Hide
|
||||
| Activity |
IC50 = 225000 nM
|
[11] | |||
| Compound Name |
2-(Benzofuran-3-ylmethyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218526; BDBM50201955
Click to Show/Hide
|
||||
| Activity |
IC50 = 225000 nM
|
[11] | |||
| Compound Name |
2-(4-Chlorobenzyl)-3-hydroxy-8-isopropylquinoline-4-carboxylicacid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL376465; SCHEMBL4185757; BDBM50201972; 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-propan-2-ylquinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 225000 nM
|
[11] | |||
| Compound Name |
2-(4-Chlorobenzyl)-8-ethyl-3-hydroxyquinoline-4-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218472; SCHEMBL4187887; BDBM50201954; 2-(4-chlorobenzyl)-8-ethyl-3-hydroxyquinoline-4-carboxylicacid; 2-[(4-chlorophenyl)methyl]-8-ethyl-3-hydroxyquinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[11] | |||
| Compound Name |
[(2S,3S,4S,5S,6S)-2-[(2S,3S,4R,5S,6R)-5-Acetamido-2-(hydroxymethyl)-6-(2-tetradecylhexadecoxy)-4-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] 5-acetamido-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303852; BDBM50422136
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[10] | |||
| Compound Name |
2-((5-Chloro-1H-indol-3-yl)methyl)-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL375391; BDBM50201969
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[11] | |||
| Compound Name |
2-(4-Chlorobenzyl)-3-(isobutoxycarbonyloxy)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219852; BDBM50201953
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[11] | |||
| Compound Name |
4-[(R)-2-Hexadecanoylamino-3-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-propionylamino]-4-methylcarbamoyl-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL135336; BDBM50067550
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[12] | |||
| Compound Name |
3-Hydroxy-2-((2-methyl-1H-indol-3-yl)methyl)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL374255; BDBM50201960
Click to Show/Hide
|
||||
| Activity |
IC50 = 270000 nM
|
[11] | |||
| Compound Name |
2-[2-([1-Phenethylcarbamoyl-2-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yl)-ethyl]-{3-[4-(4-phenoxy-phenoxy)-phenyl]-propionyl}-amino)-acetylamino]-pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL305870; BDBM50071590
Click to Show/Hide
|
||||
| Activity |
IC50 = 283000 nM
|
[8] | |||
| Compound Name |
3-(4-{4-[4-(2-Carboxy-vinyl)-phenyl]-5-[4-(2-dodecylcarbamoyl-vinyl)-phenyl]-1H-imidazol-2-yl}-phenyl)-isoxazole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL63898; SCHEMBL7993313; BDBM50100508
Click to Show/Hide
|
||||
| Activity |
IC50 = 290000 nM
|
[3] | |||
| Compound Name |
Sodium;[(2S,3S,4S,5S,6S)-2-[(2S,3R,4R,5S,6R)-5,6-dihydroxy-2-(hydroxymethyl)-4-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215391
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[14] | |||
| Compound Name |
Sodium;3,5-dihydroxy-2-[5-hydroxy-2-(hydroxymethyl)-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-4-sulfonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL60263
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[10] | |||
| Compound Name |
2-[3-[5-[5-[3-[3-(Carboxymethyl)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]pentyl]-2-[(2R,3S,4R,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303890; BDBM50422284
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[7] | |||
| Compound Name |
8-(Sec-butyl)-2-(4-chlorobenzyl)-3-hydroxyquinoline-4-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219310; SCHEMBL4191926; BDBM50201979; 8-(sec-butyl)-2-(4-chlorobenzyl)-3-hydroxyquinoline-4-carboxylicacid; 8-butan-2-yl-2-[(4-chlorophenyl)methyl]-3-hydroxyquinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[11] | |||
| Compound Name |
2-(4-Chlorobenzyl)-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL217974; SCHEMBL4187713; BDBM50201962; 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic Acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 325000 nM
|
[11] | |||
| Compound Name |
3-Hydroxy-2-(1H-indol-3-ylmethyl)-8-(3-thienyl)quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL426171; BDBM50201970
Click to Show/Hide
|
||||
| Activity |
IC50 = 380000 nM
|
[11] | |||
| Compound Name |
Chembl413369
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215417; BDBM50288834
Click to Show/Hide
|
||||
| Activity |
IC50 = 380000 nM
|
[15] | |||
| Compound Name |
2-[(4-Chlorophenyl)methyl]-3-phenylmethoxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL376211; BDBM50201985; 3-(benzyloxy)-2-(4-chlorobenzyl)-7,8,9,10-tetrahydrobenzo[h]-quinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 390000 nM
|
[11] | |||
| Compound Name |
2-(4-Chlorobenzyl)-3-(methoxycarbonyloxy)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218611; BDBM50201997
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[11] | |||
| Compound Name |
3-Hydroxy-2-((5-methoxy-1H-indol-3-yl)methyl)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218559; BDBM50201964
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[11] | |||
| Compound Name |
2-[3-[5-[7-[3-[3-(Carboxymethyl)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]heptyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303886; BDBM50422285
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[7] | |||
| Compound Name |
3-Hydroxy-2-(thiophen-2-ylmethyl)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL373617; SCHEMBL1292167; BDBM50201987; 3-hydroxy-2-(thiophen-2-ylmethyl)-7,8,9,10-tetrahydrobenzo-[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 413000 nM
|
[11] | |||
| Compound Name |
2-Benzyl-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL384767; SCHEMBL1292134; BDBM50201977
Click to Show/Hide
|
||||
| Activity |
IC50 = 413000 nM
|
[11] | |||
| Compound Name |
3-Hydroxy-2-(1H-indol-3-ylmethyl)-8-isopropylquinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL373616; BDBM50201956
Click to Show/Hide
|
||||
| Activity |
IC50 = 415000 nM
|
[11] | |||
| Compound Name |
8-Bromo-2-(4-chlorobenzyl)-3-hydroxyquinoline-4-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219705; SCHEMBL4188226; BDBM50201994; 8-bromo-2-(4-chlorobenzyl)-3-hydroxyquinoline-4-carboxylicacid; 8-bromo-2-[(4-chlorophenyl)methyl]-3-hydroxyquinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 425000 nM
|
[11] | |||
| Compound Name |
3-Hydroxy-2-phenethyl-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220251; SCHEMBL1292184; BDBM50201951; 3-hydroxy-2-(2-phenylethyl)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 450000 nM
|
[11] | |||
| Compound Name |
3-Hydroxy-2-(thiophen-3-ylmethyl)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL373495; SCHEMBL1292061; BDBM50201963; 3-hydroxy-2-(thiophen-3-ylmethyl)-7,8,9,10-tetrahydrobenzo-[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 475000 nM
|
[11] | |||
| Compound Name |
2-Methyl-3-[2-(3,4,5-trihydroxy-phenyl)-acetylamino]-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220046; BDBM50205387
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[4] | |||
| Compound Name |
2-(4-Cyano-benzyl)-3-hydroxy-7,8,9,10-tetrahydro-benzo[h]quinoline-4-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL376297; SCHEMBL2250208; BDBM50201961; 2-(4-cyanobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]-quinoline-4-carboxylic acid; 2-[(4-cyanophenyl)methyl]-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[11] | |||
| Compound Name |
2-[3-[2-[(2R,3S,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL375429; SCHEMBL7029910; ZINC3823372; BDBM50205388; [3-[2-(alpha-D-Mannopyranosyloxy)phenyl]phenyl]acetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[4] | |||
| Compound Name |
2-(4-Chlorobenzyl)-3-hydroxy-9-(isopropylsulfonyl)-7,8,9,10-tetrahydro-1,9-phenanthroline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218470; SCHEMBL2251334; BDBM50201990
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[11] | |||
| Compound Name |
2-[3-[5-[3-[3-[3-[3-[3-(Carboxymethyl)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]propylsulfanyl]propylsulfanyl]propyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303872; BDBM50422279
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[7] | |||
| Compound Name |
(2R)-2-[(2S,3R,4S,5S,6R)-3-Benzoyloxy-2-[(2R,3R)-1,4-dimethoxy-1,4-dioxo-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3335527; BDBM50026869
Click to Show/Hide
|
||||
| Activity |
IC50 = 520000 nM
|
[6] | |||
| Compound Name |
2-[3-[4-[6-[3-[3-(Carboxymethoxy)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]hexyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenoxy]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303882; BDBM50422291
Click to Show/Hide
|
||||
| Activity |
IC50 = 540000 nM
|
[7] | |||
| Compound Name |
3-Acetoxy-2-(4-chlorobenzyl)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL426704; BDBM50201982
Click to Show/Hide
|
||||
| Activity |
IC50 = 545000 nM
|
[11] | |||
| Compound Name |
3-Hydroxy-2-phenyl-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL373931; SCHEMBL1292423; BDBM50201957
Click to Show/Hide
|
||||
| Activity |
IC50 = 550000 nM
|
[11] | |||
| Compound Name |
2-(4-Chlorobenzyl)-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219429; SCHEMBL4187900; BDBM50201968; 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)quinoline-4-carboxylic Acid; 4-Quinolinecarboxylic acid,2-[(4-chlorophenyl)methyl]-3-hydroxy-8-(trifluoromethoxy)-
Click to Show/Hide
|
||||
| Activity |
IC50 = 550000 nM
|
[11] | |||
| Compound Name |
Sodium;[(2S,3R,4R,5R,6R)-2,4,5-trihydroxy-6-[(2R,3S,4R)-2-(hydroxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxyoxan-3-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL177316
Click to Show/Hide
|
||||
| Activity |
IC50 = 560000 nM
|
[16] | |||
| Compound Name |
8-(4-Chlorobenzyl)-7-hydroxy-2,3-dihydro-1H-9-aza-cyclopenta[a]naphthalene-6-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219280; SCHEMBL2252154; BDBM50201981; 2-[(4-chlorophenyl)methyl]-3-hydroxy-8,9-dihydro-7H-cyclopenta[h]quinoline-4-carboxylic acid; 8-(4-chlorobenzyl)-7-hydroxy-2,3-dihydro-1H-9-aza-cyclopenta-[a]naphthalene-6-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 580000 nM
|
[11] | |||
| Compound Name |
Chembl264987
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215419; BDBM50288839
Click to Show/Hide
|
||||
| Activity |
IC50 = 600000 nM
|
[15] | |||
| Compound Name |
3-Hydroxy-2-(4-(trifluoromethoxy)benzyl)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219284; SCHEMBL1292391; BDBM50201975
Click to Show/Hide
|
||||
| Activity |
IC50 = 610000 nM
|
[11] | |||
| Compound Name |
2-(4-Chlorobenzyl)-3-hydroxy-9-(methylsulfonyl)-7,8,9,10-tetrahydro-1,9-phenanthroline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218469; SCHEMBL1292783; BDBM50201980
Click to Show/Hide
|
||||
| Activity |
IC50 = 625000 nM
|
[11] | |||
| Compound Name |
6-Bromo-2-(4-chlorobenzyl)-3-hydroxyquinoline-4-carboxylicacid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218020; BDBM50201971
Click to Show/Hide
|
||||
| Activity |
IC50 = 650000 nM
|
[11] | |||
| Compound Name |
Sodium;[(2S,3R,4R,5R,6R)-2,4,5-trihydroxy-6-[(2R,3R,4R,5S)-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxyoxan-3-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL362419
Click to Show/Hide
|
||||
| Activity |
IC50 = 670000 nM
|
[16] | |||
| Compound Name |
2-[3-[5-[[4-[4-[[3-[3-(Carboxymethyl)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl]phenoxy]phenyl]methyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303891; BDBM50422283
Click to Show/Hide
|
||||
| Activity |
IC50 = 700000 nM
|
[7] | |||
| Compound Name |
Chembl446630
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215427; BDBM50291309
Click to Show/Hide
|
||||
| Activity |
IC50 = 700000 nM
|
[13] | |||
| Compound Name |
8-Chloro-2-(4-chlorobenzyl)-3-hydroxyquinoline-4-carboxylicacid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219706; BDBM50201992
Click to Show/Hide
|
||||
| Activity |
IC50 = 715000 nM
|
[11] | |||
| Compound Name |
(2R)-2-[(2S,3R,4S,5S,6R)-2-[(2R,3R)-1,4-Dimethoxy-1,4-dioxo-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2204273; BDBM50400721
Click to Show/Hide
|
||||
| Activity |
IC50 = 880000 nM
|
[6] | |||
| Compound Name |
7-Chloro-2-(4-chlorobenzyl)-3-hydroxyquinoline-4-carboxylicacid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218244; BDBM50201952
Click to Show/Hide
|
||||
| Activity |
IC50 = 900000 nM
|
[11] | |||
| Compound Name |
(2S,4R,5R,6R)-5-Acetamido-2-[(2S,3S,4S,5S,6S)-2-[(2S,3S,4R,5S,6R)-5-acetamido-6-[6-[[3-carboxy-4-(3-hydroxy-6-oxoxanthen-9-yl)phenyl]carbamothioylamino]hexoxy]-2-(hydroxymethyl)-4-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215418; BDBM50214503
Click to Show/Hide
|
||||
| Activity |
IC50 = 900000 nM
|
[15] | |||
| Compound Name |
(2R)-2-[(2S,3R,4R,5S,6R)-2-[(2R,3R)-1,4-Dimethoxy-1,4-dioxo-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-3-hydroxy-6-(hydroxymethyl)-5-(naphthalene-1-carbonyloxy)oxan-4-yl]oxy-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2204271; BDBM50400719
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[17] | |||
| Compound Name |
2-[3-[5-[4-[4-[3-[1-[4-[3-[3-(Carboxymethyl)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]butanoyl]piperidin-4-yl]propyl]piperidin-1-yl]-4-oxobutyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303875; BDBM50422292
Click to Show/Hide
|
||||
| Activity |
IC50 = 1000000 nM
|
[7] | |||
| Compound Name |
(2S,4R,5R,6R)-5-Acetamido-2-[(2S,3S,4S,5S,6S)-2-[(2S,3S,4R,5S)-5-acetamido-6-hydroxy-2-(hydroxymethyl)-4-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215390
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[14] | |||
| Compound Name |
2-[3-[5-[6-[3-[2-(Carboxymethyl)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-6-oxohexanoyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303868; BDBM50422282
Click to Show/Hide
|
||||
| Activity |
IC50 = 1000000 nM
|
[7] | |||
| Compound Name |
2-(4-Chlorobenzyl)-3-hydroxy-8-methylquinoline-4-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218471; SCHEMBL4183673; BDBM50201986; 2-(4-chlorobenzyl)-3-hydroxy-8-methylquinoline-4-carboxylicacid; 2-[(4-chlorophenyl)methyl]-3-hydroxy-8-methylquinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 1000000 nM
|
[11] | |||
| Compound Name |
5-Acetylamino-2-{3,5-dihydroxy-2-hydroxymethyl-6-[2-hydroxymethyl-4-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-4-yloxy}-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL367520; BDBM50050458
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[18] | |||
| Compound Name |
Sialyl-Lewis X
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3'-Sialyl-Lewis X; sialyl LewisX; Sialyl lewis-x; Sialyl Lex tri; 3'-Sialyl-Lewis-X tetrasaccharide; Sialyl LeX; 3'-SIALYL LEWIS X; 3'-SLeX; SSEA 1; UNII-0PS35WG8U3; 0PS35WG8U3; a-NeuNAc-(2>3)-b-D-Gal-(1>4)(a-L-Fuc-[1>3])-D-GlcNAc; 3-Sialyl Lewis X; SCHEMBL346849; CHEMBL375586; DTXSID60913167; BDBM50450369; ZINC96129530; HY-W020790; CS-0031944; J3.549.354I; Q3959958; W-204175; alpha-NeuNAc-(2>3)-beta-delta-Gal-(1>4)(a-L-Fuc-[1>3])-delta-GlcNAc
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[19] | |||
| Compound Name |
2-[3-[2-[(2R,3S,4R,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-[6-[4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]hexyl]phenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303879; BDBM50422286
Click to Show/Hide
|
||||
| Activity |
IC50 = 1000000 nM
|
[7] | |||
| Compound Name |
Sodium;[(2S,3R,4R,5R,6R)-2,4,5-trihydroxy-6-[(2R,3S,4R)-2-(hydroxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxyoxan-3-yl] hydrogen phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL175724
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[16] | |||
| Compound Name |
5-(2-{3,5-Dihydroxy-2-hydroxymethyl-6-[2-hydroxymethyl-4-(2,3,4-trihydroxy-5-methoxy-hexyloxy)-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-4-yloxy}-acetylamino)-2,4-dihydroxy-6-(1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL175649; BDBM50050456
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[18] | |||
| Compound Name |
Chembl154747
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215428; BDBM50291310
Click to Show/Hide
|
||||
| Activity |
IC50 = 1000000 nM
|
[13] | |||
| Compound Name |
2-[(2S,3R,4S,5S,6R)-2-[(2R,3R)-1,4-Dimethoxy-1,4-dioxo-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxybutan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxyacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2204274; BDBM50400722
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[17] | |||
| Compound Name |
Sodium;[(2S,3R,4R,5R,6R)-6-[(2R,3S,4R,5S)-5-acetamido-2-(hydroxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-2,4,5-trihydroxyoxan-3-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL177789
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[16] | |||
| Compound Name |
2-(4-Carbamoylbenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo-[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220305; SCHEMBL1292066; BDBM50201996; 2-[(4-carbamoylphenyl)methyl]-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 1250000 nM
|
[11] | |||
| Compound Name |
Chembl405132
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215423; BDBM50288835
Click to Show/Hide
|
||||
| Activity |
IC50 = 1500000 nM
|
[15] | |||
| Compound Name |
3-Hydroxy-7,8-dimethyl-2-phenylquinoline-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218311; CTK3F8504; DTXSID00582750; BDBM50201924; 4-Quinolinecarboxylic acid, 3-hydroxy-7,8-dimethyl-2-phenyl-
Click to Show/Hide
|
||||
| Activity |
IC50 = 1500000 nM
|
[11] | |||
| Compound Name |
2-[3-[2-[(2R,3S,4R,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-[2-[3-[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]ethyl]phenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303893; BDBM50422280
Click to Show/Hide
|
||||
| Activity |
IC50 = 2000000 nM
|
[7] | |||
| Compound Name |
(2S,4R,5R,6R)-5-Acetamido-2-[(2S,3S,4S,5S,6S)-2-[(2S,3S,4R,5S,6R)-5-acetamido-6-(6-aminohexoxy)-2-(hydroxymethyl)-4-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215422; BDBM50214505
Click to Show/Hide
|
||||
| Activity |
IC50 = 2000000 nM
|
[13] | |||
| Compound Name |
2-[3-[5-[[4-[[3-[3-(Carboxymethyl)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl]phenyl]methyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303888; BDBM50422295
Click to Show/Hide
|
||||
| Activity |
IC50 = 2000000 nM
|
[7] | |||
| Compound Name |
2-[[4-[2-[(2R,3S,4R,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]benzoyl]amino]butanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303951; BDBM50422122
Click to Show/Hide
|
||||
| Activity |
IC50 = 2000000 nM
|
[20] | |||
| Compound Name |
2-[3-[5-[6-[3-[2-(Carboxymethyl)phenyl]-4-hydroxyphenyl]hexyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303874; BDBM50422289
Click to Show/Hide
|
||||
| Activity |
IC50 = 2000000 nM
|
[7] | |||
| Compound Name |
3-(2,2-Difluoro-2-((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1086922; BDBM50313791
Click to Show/Hide
|
||||
| Activity |
IC50 = 2500000 nM
|
[21] | |||
| Compound Name |
2-[3-[5-[4-[3-[3-(Carboxymethyl)phenyl]-4-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]butyl]-2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303873; BDBM50422293
Click to Show/Hide
|
||||
| Activity |
IC50 = 2500000 nM
|
[7] | |||
| Compound Name |
2-[3-[2-[(2R,3S,4R,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303887; BDBM50422131
Click to Show/Hide
|
||||
| Activity |
IC50 = 2600000 nM
|
[7] | |||
| Compound Name |
2-{{2-[6-(4-{2-[2-(2-Ethoxy-ethoxy)-ethoxy]-ethoxy}-butoxymethyl)-3,4,5-trihydroxy-tetrahydro-pyran-2-yl]-acetyl}-[1-(methoxycarbonylmethyl-carbamoyl)-ethyl]-amino}-pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL74108; BDBM50071583
Click to Show/Hide
|
||||
| Activity |
IC50 > 3000000 nM
|
[8] | |||
| Compound Name |
2-{2-[6-(4-{2-[2-(2-Ethoxy-ethoxy)-ethoxy]-ethoxy}-butoxymethyl)-3,4,5-trihydroxy-tetrahydro-pyran-2-yl]-acetylamino}-pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77834; BDBM50071596
Click to Show/Hide
|
||||
| Activity |
IC50 > 3000000 nM
|
[8] | |||
| Compound Name |
(S)-2-(2,2-Difluoro-2-((2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1086779; BDBM50313788
Click to Show/Hide
|
||||
| Activity |
IC50 = 3000000 nM
|
[21] | |||
| Compound Name |
2-[3-[2-[(2R,3S,4R,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenoxy]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303942; BDBM50422125
Click to Show/Hide
|
||||
| Activity |
IC50 = 4900000 nM
|
[20] | |||
| Compound Name |
3-(2,2-Difluoro-2-((2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1087806; BDBM50313789
Click to Show/Hide
|
||||
| Activity |
IC50 = 5000000 nM
|
[21] | |||
| Compound Name |
(2S,4S,5R,6R)-5-Acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R)-5-acetamido-1,2-dihydroxy-6-oxo-4-[(2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyhexan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2368729
Click to Show/Hide
|
||||
| Activity |
IC50 > 5000000 nM
|
[21] | |||
| Compound Name |
3-(2,2-Difluoro-2-((2R,3S,4S,5S,6R)-2,3,4,5-tetrahydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1086778; BDBM50313787
Click to Show/Hide
|
||||
| Activity |
IC50 = 6500000 nM
|
[21] | |||
| Compound Name |
2-[2,6-Dimethyl-4-[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenoxy]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303929; BDBM50422128
Click to Show/Hide
|
||||
| Activity |
IC50 = 6900000 nM
|
[20] | |||
| Compound Name |
(3R,5R)-3,4,5-Trihydroxy-1-[[4-[2-(trifluoromethyl)phenyl]phenyl]methoxy]cyclohexane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL365848; BDBM50169053; (3R,5R)-3,4,5-Trihydroxy-1-(2''-trifluoromethyl-biphenyl-4-ylmethoxy)-cyclohexanecarboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 10000000 nM
|
[22] | |||
| Compound Name |
(S)-2-(2,2-Difluoro-2-((2R,3S,4S,5S,6R)-2,3,4,5-tetrahydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1077187; BDBM50313786
Click to Show/Hide
|
||||
| Activity |
IC50 = 11000000 nM
|
[21] | |||
| Compound Name |
(S)-2-(2,2-Difluoro-2-((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)acetamido)pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1077185; BDBM50313790
Click to Show/Hide
|
||||
| Activity |
IC50 = 11000000 nM
|
[21] | |||
| Compound Name |
2-[4-Methyl-3-[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenoxy]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303939; BDBM50422116
Click to Show/Hide
|
||||
| Activity |
IC50 = 12000000 nM
|
[20] | |||
| Compound Name |
(1S,3R,4S,5R)-4-Acetamido-1-[(2S,3S,4S,5R,6S)-2-[(2S,3S,4R,5S,6R)-5-acetamido-6-hydroxy-2-(hydroxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3-hydroxy-5-[(1S,2R)-1,2,3-trihydroxypropyl]cyclohexane-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215473
Click to Show/Hide
|
||||
| Activity |
IC50 = 12000000 nM
|
[23] | |||
| Compound Name |
Ethoxy-[3-[3-[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]propyl]phosphinic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303949; BDBM50422119
Click to Show/Hide
|
||||
| Activity |
IC50 = 12400000 nM
|
[20] | |||
| Compound Name |
2-Phenyl-2-[3-[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenoxy]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303933; BDBM50422134
Click to Show/Hide
|
||||
| Activity |
IC50 = 17000000 nM
|
[20] | |||
| Compound Name |
(2S)-3-Methyl-2-[[(3R,5R)-1,3,4,5-tetrahydroxycyclohexanecarbonyl]amino]pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL190494; BDBM50168307; 3-Methyl-2-[((3R,5R)-1,3,5-trihydroxy-4-(S)-hydroxy-cyclohexanecarbonyl)-amino]-pentanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 19000000 nM
|
[23] | |||
| Compound Name |
(2S)-3-Hydroxy-2-[[(3R,5R)-1,3,4,5-tetrahydroxycyclohexanecarbonyl]amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL193022; BDBM50168303; 3-Hydroxy-2-[((3R,5R)-1,3,5-trihydroxy-4-(S)-hydroxy-cyclohexanecarbonyl)-amino]-propionic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 19500000 nM
|
[23] | |||
| Compound Name |
2-[4-[2-[(2R,3S,4R,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenoxy]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303952; BDBM50422120
Click to Show/Hide
|
||||
| Activity |
IC50 = 20000000 nM
|
[20] | |||
| Compound Name |
2-[3-[2-[(2R,3S,4R,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303935; BDBM50422130
Click to Show/Hide
|
||||
| Activity |
IC50 = 20000000 nM
|
[20] | |||
| Compound Name |
(S)-2-[((3R,5R)-1,3,4,5-Tetrahydroxy-cyclohexanecarbonyl)-amino]-pentanedioic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL191224; BDBM50168306
Click to Show/Hide
|
||||
| Activity |
IC50 = 21000000 nM
|
[23] | |||
| Compound Name |
4-[((3R,5R)-1,3,4,5-Tetrahydroxy-cyclohexanecarbonyl)-amino]-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL192006; BDBM50168305
Click to Show/Hide
|
||||
| Activity |
IC50 = 40000000 nM
|
[23] | |||
| Compound Name |
6-[((R)-(R)-1,3,4,5-Tetrahydroxy-cyclohexanecarbonyl)-amino]-hexanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL192087; BDBM50168309
Click to Show/Hide
|
||||
| Activity |
IC50 > 50000000 nM
|
[23] | |||
| Compound Name |
((3R,5R)-1,3,4,5-Tetrahydroxy-cyclohexanecarbonyl)-carbamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL363472; BDBM50168308
Click to Show/Hide
|
||||
| Activity |
IC50 > 50000000 nM
|
[23] | |||
| Compound Name |
(2S)-2-[[(3R,5R)-1,3,4,5-Tetrahydroxycyclohexanecarbonyl]amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL190092; BDBM50168304; 2-[((3R,5R)-1,3,5-Trihydroxy-4-(S)-hydroxy-cyclohexanecarbonyl)-amino]-propionic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 50000000 nM
|
[23] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of 2-[1-(4-chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid (PSI-421), a P-selectin inhibitor with improved pharmacokinetic properties and oral efficacy in models of vascular injury. J Med Chem. 2010 Aug 26;53(16):6003-17. | ||||
| REF 2 | Sulfated galactocerebrosides as potential antiinflammatory agents. J Med Chem. 1997 Sep 26;40(20):3234-47. | ||||
| REF 3 | Development of potent non-carbohydrate imidazole-based small molecule selectin inhibitors with antiinflammatory activity. J Med Chem. 2001 Jun 21;44(13):2094-107. | ||||
| REF 4 | Rational design of novel, potent small molecule pan-selectin antagonists. J Med Chem. 2007 Mar 22;50(6):1101-15. | ||||
| REF 5 | Design and synthesis of an alpha-mannosyl terpenoid as selective inhibitor of P-selectin. Bioorg Med Chem Lett. 1997 Oct 7;7(19):2485-90. | ||||
| REF 6 | Acyclic tethers mimicking subunits of polysaccharide ligands: selectin antagonists. ACS Med Chem Lett. 2014 Jul 16;5(9):1054-9. | ||||
| REF 7 | Novel synthetic inhibitors of selectin-mediated cell adhesion: synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-alpha-D- mannopyranosyloxy)phenyl]hexane (TBC1269). J Med Chem. 1998 Mar 26;41(7):1099-111. | ||||
| REF 8 | Synthesis of sialyl Lewis X mimetics using the Ugi four-component reaction. Bioorg Med Chem Lett. 1998 Sep 8;8(17):2333-8. | ||||
| REF 9 | Optimization of highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1051-5. | ||||
| REF 10 | Studies on selectin blockers. 2. Novel selectin blocker as potential therapeutics for inflammatory disorders. J Med Chem. 1996 May 10;39(10):2055-9. | ||||
| REF 11 | 2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[H]quinoline-4-carboxylic acid (PSI-697): identification of a clinical candidate from the quinoline salicylic acid series of P-selectin antagonists. J Med Chem. 2007 Jan 11;50(1):40-64. | ||||
| REF 12 | Studies on selectin blockers. 7. Structure-activity relationships of sialyl Lewis X mimetics based on modified Ser-Glu dipeptides. J Med Chem. 1998 Oct 22;41(22):4279-87. | ||||
| REF 13 | Chemical and enzymatic synthesis of high-affinity selectin ligands. Bioorg Med Chem Lett. 1997 Mar 4;7(5):577-80. | ||||
| REF 14 | Selectin-ligand interactions revealed by molecular dynamics simulation in solution. J Med Chem. 1997 Jan 31;40(3):362-9. | ||||
| REF 15 | Synthesis and biological activity of novel sialyl-lewisX conjugates. Bioorg Med Chem Lett. 1996 Mar 5;6(5):509-14. | ||||
| REF 16 | Studies on selectin blocker. 1. Structure-activity relationships of sialyl Lewis X analogs. J Med Chem. 1996 Mar 15;39(6):1339-43. | ||||
| REF 17 | A new approach to explore the binding space of polysaccharide-based ligands: selectin antagonists. ACS Med Chem Lett. 2012 Oct 11;3(12):1045-9. | ||||
| REF 18 | Studies on selectin blocker. 3. Investigation of the carbohydrate ligand sialyl Lewis X recognition site of P-selectin. J Med Chem. 1996 Nov 8;39(23):4547-53. | ||||
| REF 19 | A solid-phase synthesis for beta-turn mimetics of sialyl Lewis X. Bioorg Med Chem Lett. 2000 Aug 21;10(16):1827-30. | ||||
| REF 20 | Rational design and synthesis of small molecule, non-oligosaccharide selectin inhibitors: (alpha-D-mannopyranosyloxy)biphenyl-substituted carboxylic acids. J Med Chem. 1995 Dec 22;38(26):4976-84. | ||||
| REF 21 | Synthesis of fluorinated C-mannopeptides as sialyl Lewisx mimics for E- and P-selectin inhibition. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1957-60. | ||||
| REF 22 | Quinic acid derivatives as sialyl Lewis(x)-mimicking selectin inhibitors: design, synthesis, and crystal structure in complex with E-selectin. J Med Chem. 2005 Jun 30;48(13):4346-57. | ||||
| REF 23 | Sialyl Lewis(x) analogs based on a quinic acid scaffold as the fucose mimic. Bioorg Med Chem Lett. 2005 Jul 1;15(13):3224-8. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.