Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T11793 | Target Info | |||
| Target Name | Cytochrome P450 2B6 (CYP2B6) | ||||
| Synonyms |
Cytochrome P450 IIB1; CYPIIB6; 1,4-cineole 2-exo-monooxygenase
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| Target Type | Literature-reported Target | ||||
| Gene Name | CYP2B6 | ||||
| Biochemical Class | Paired donor oxygen oxidoreductase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 73 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Thiotepa
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Approved | Compound Info | ||
| Synonyms |
thiotepa; THIO-TEPA; 52-24-4; Triethylenethiophosphoramide; Thiophosphamide; Tiofosyl; Tiofosfamid; Thiofozil; Tiofozil; Thioplex; Tespamin; Oncotepa; Tespamine; Girostan; Thiotef; Stepa; Tio-tef; Thio-Tep; Oncotiotepa; Tifosyl; Oncothio-tepa; TESPA; TSPA; Thio-tepa S; Ledertepa; Thiotriethylenephosphoramide; TIO TEF; N,N',N''-Triethylenethiophosphoramide; Tris(1-aziridinyl)phosphine sulfide; Thiophosphamidum; 1,1',1''-phosphorothioyltriaziridine; Triethylene thiophosphoramide; Triaziridinylphosphine sulfide
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| Activity |
Ki = 50000 nM
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[1] | |||
| Compound Name |
BAY 1021189
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Approved | Compound Info | ||
| Synonyms |
Vericiguat; 1350653-20-1; UNII-LV66ADM269; BAY-1021189; Methyl (4,6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate; BAY1021189; LV66ADM269; MK-1242; Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate; methyl N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate; Methyl (4,6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)pyrimidin-5-yl)carbam
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| Activity |
IC50 ~ 50000 nM
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[2] | |||
| Compound Name |
Saxagliptin
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Approved | Compound Info | ||
| Synonyms |
Onglyza; BMS 477118-11; BMS-477118; Kombiglyze XR (TN); OPC-262; Onglyza (TN); BMS-477118-11; (1S,5S)-2-[2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile; 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-amino(3-hydroxytricyclo[3.3
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| Activity |
IC50 ~ 50000 nM
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[3] | |||
| Compound Name |
Ticlopidine
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Approved | Compound Info | ||
| Synonyms |
Ticlid; Ticlopidina; Ticlopidinum; PCR 5332; Ticlid (TN); Ticlopidin-Puren; Ticlopidina [INN-Spanish]; Ticlopidine (INN); Ticlopidine [INN:BAN]; Ticlopidinum [INN-Latin]; Ticlopidin-Puren (TN); 5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine; 5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine; 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine; 5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
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| Activity |
IC50 = 70000 nM
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[4] | |||
| Compound Name |
Dolutegravir
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Approved | Compound Info | ||
| Synonyms |
1051375-16-6; GSK1349572; Tivicay; S/GSK1349572; Dolutegravir (GSK1349572); S-349572; GSK-1349572; GSK 1349572; UNII-DKO1W9H7M1; (4r,12as)-N-(2,4-Difluorobenzyl)-7-Hydroxy-4-Methyl-6,8-Dioxo-3,4,6,8,12,12a-Hexahydro-2h-Pyrido[1',2':4,5]pyrazino[2,1-B][1,3]oxazine-9-Carboxamide; CHEBI:76010; DKO1W9H7M1; Tivicay (TN); (4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide; Dolutegravir Sodium (
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| Activity |
IC50 ~ 100000 nM
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[5] | |||
| Compound Name |
Carbamazepine
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Approved | Compound Info | ||
| Synonyms |
Carbamazepine (iv, epilepsy); Carbamazepine (iv, epilepsy), Lundbeck; Carbamazepine (iv, epilepsy), Ovation Pharmaceuticals
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| Activity |
EC50 = 145000 nM
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[6] | |||
| Compound Name |
PT2385
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Phase 2 | Compound Info | ||
| Synonyms |
ONBSHRSJOPSEGS-INIZCTEOSA-N; PT-2385; UNII-6O16716DXP; 1672665-49-4; 6O16716DXP; SCHEMBL16555810; ZINC230453533; AKOS030526641; HY-12867; PT2385,1672665-49-4, PT 2385,PT-2385; Benzonitrile, 3-(((1S)-2,2-difluoro-2,3-dihydro-1-hydroxy-7-(methylsulfonyl)-1H-inden-4-yl)oxy)-5-fluoro-; 3-{[(1s)-2,2-Difluoro-1-Hydroxy-7-(Methylsulfonyl)-2,3-Dihydro-1h-Inden-4-Yl]oxy}-5-Fluorobenzonitrile; 3-(((1S)-2,2-Difluoro-1-hydroxy-7-methanesulfonyl-2,3-dihydro-1hinden-4-yl)oxy)-5-fluorobenzonitrile; 79A
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
Tariquidar
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Discontinued in Phase 2 | Compound Info | ||
| Synonyms |
Tariquidarth; XR 9576; XR9576; Tariquidar (USAN/INN); N-[2-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-4,5-dimethoxyphenyl]quinoline-3-carboxamide; N-(2-((4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)carbamoyl)-4,5-dimethoxyphenyl)quinoline-3-carboxamide
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| Activity |
IC50 ~ 100000 nM
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[8] | |||
| Compound Name |
3-(6-Methoxynaphthalen-2-yl)pyridin-4-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL453169; 3-(6-Methoxynaphthalen-2-yl)pyridin-4-amine; ZINC40835651; BDBM50272248
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| Activity |
IC50 ~ 50000 nM
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[9] | |||
| Compound Name |
3-(pyridin-3-yl)prop-2-yn-1-amine
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Investigative | Compound Info | ||
| Synonyms |
3-(pyridin-3-yl)prop-2-yn-1-amine; 777856-62-9; 2-PROPYN-1-AMINE, 3-(3-PYRIDINYL)-; CHEMBL360541; SCHEMBL3603698; CTK2G6074; BDBM12348; DTXSID90460412; MolPort-014-472-743; BGKUWZFWNZFRMO-UHFFFAOYSA-N; ZINC13607158; nicotine 3-heteroaromatic analogue 3a; AKOS010148504; MCULE-3042424640; NE58716; US8609708, 3; Z1333761438
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| Activity |
Ki = 82500 nM
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[10] | |||
| Compound Name |
(5-(pyridin-3-yl)furan-2-yl)methanamine
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Investigative | Compound Info | ||
| Synonyms |
(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE; [5-(pyridin-3-yl)furan-2-yl]methanamine; (5-pyridin-3-ylfuran-2-yl)methanamine; 1-(5-pyridin-3-ylfuran-2-yl)methanamine; CHEMBL178090; CHEBI:41804; (5-Pyridin-3-yl-2-furyl)methylamine; 837376-48-4; 2-Furanmethanamine, 5-(3-pyridinyl)-; SCHEMBL1791769; GTPL8754; BDBM12345; MolPort-022-593-431; ZINC13607134; nicotine 3-heteroaromatic analogue 2a; AKOS022808436; DB07621; compound 39a [PMID: 15634016]; D3G; US8609708, 2; US8609708, 47; F2167-0893
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| Activity |
Ki = 95500 nM
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[10] | |||
| Compound Name |
6-Isoquinolin-4-yl-3,4-dihydroquinolin-2(1H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL456390; 6-Isoquinolin-4-yl-3,4-dihydroquinolin-2(1H)-one; SCHEMBL1120250; BDBM50273813
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| Activity |
IC50 = 100000 nM
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[11] | |||
| Compound Name |
1-[5-(6-Methoxynaphthalen-2-yl)pyridin-3-yl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL502824; BDBM50272291
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| Activity |
IC50 ~ 50000 nM
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[9] | |||
| Compound Name |
5-Amino-N-[[4-(2-fluoropyridin-3-yl)phenyl]methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4091821; SCHEMBL15222561; BDBM50249403
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| Activity |
EC50 ~ 50000 nM
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[12] | |||
| Compound Name |
10-[(3S)-1-Azabicyclo[2.2.2]octan-3-yl]-6-methoxy-1,2,10-triazatricyclo[6.4.1.04,13]trideca-2,4(13),5,7-tetraen-9-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3261485; SCHEMBL1077301; BDBM50014554
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| Activity |
IC50 ~ 50000 nM
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[13] | |||
| Compound Name |
HIF-2alpha-IN-1
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4175320; SCHEMBL16846977; US9884843, Compound 3; US9884843, Compound 43; BDBM282572; ZINC521836526; CS-5544; HY-19949; HIF-2AfAE'A centa' notA inverted exclamation markAfasA'A; AfAE'Adaggeratrade mark?-IN-1
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
1H-Benzimidazole, 6-methoxy-2-(propylthio)-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2018905; BDBM50380519; AKOS001174994; 2-(Propylthio)-6-methoxy-1H-benzoimidazole; J3.516.539H; 6-methoxy-2-(propylsulfanyl)-1H-1,3-benzodiazole
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| Activity |
IC50 = 50000 nM
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[14] | |||
| Compound Name |
2-(Butylthio)-6-methoxy-1H-benzoimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2018903; BDBM50380520; J3.516.540A
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| Activity |
IC50 = 50000 nM
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[14] | |||
| Compound Name |
2-Benzylsulfanyl-6-methoxy-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2018915; SCHEMBL4650009; ZINC6786825; 5-methoxy-2-benzylthio-benzimidazole; BDBM50380529; AKOS001258354; MCULE-6127505314; 2-(benzylsulfanyl)-6-methoxy-1H-1,3-benzodiazole; Z16077936
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| Activity |
IC50 = 50000 nM
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[14] | |||
| Compound Name |
6-Methoxy-2-(2-methylpropylsulfanyl)-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2018909; BDBM50380523
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| Activity |
IC50 = 50000 nM
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[14] | |||
| Compound Name |
Chembl4203179
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL18288802; BDBM50458024
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| Activity |
IC50 ~ 50000 nM
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[15] | |||
| Compound Name |
4-[(5-Methoxybenzimidazol-2-ylthio)methyl]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2018922; Oprea1_174290; SCHEMBL1065421; ZINC3848073; BDBM50380533; AKOS000101026; ST049297
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| Activity |
IC50 = 50000 nM
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[14] | |||
| Compound Name |
2-{[4-(Tert-butyl)phenyl]methylthio}-5-methoxybenzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2018918; Oprea1_177885; Oprea1_217669; ZINC273332; BDBM50380532; AKOS000560374; MCULE-9586513461; UPCMLD0ENAT0502-4466:001; ST50338349
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| Activity |
IC50 = 50000 nM
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[14] | |||
| Compound Name |
6-Methoxy-2-[(4-phenylmethoxyphenyl)methylsulfanyl]-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2018926; BDBM50380511
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| Activity |
IC50 = 50000 nM
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[14] | |||
| Compound Name |
10-[(3S)-1-Azabicyclo[2.2.2]octan-3-yl]-6-fluoro-1,2,10-triazatricyclo[6.4.1.04,13]trideca-2,4(13),5,7-tetraen-9-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3261482; SCHEMBL1078926; BDBM50014551
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| Activity |
IC50 ~ 50000 nM
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[13] | |||
| Compound Name |
6-Methoxy-2-(pyridin-2-ylmethylsulfanyl)-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2019022; SCHEMBL7851440; SCHEMBL11686394; ZINC6621682; BDBM50380512; AKOS001309032; AKOS016896932; MCULE-9063567896; ST51029295; 5-methoxy-2-(2-pyridylmethylthio)benzimidazole; 5-methoxy-2-[(pyridin-2-ylmethyl)thio]-1H-benzimidazole
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| Activity |
IC50 = 50000 nM
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[14] | |||
| Compound Name |
Chembl4128835
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Investigative | Compound Info | ||
| Synonyms |
BDBM50272591
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| Activity |
IC50 ~ 50000 nM
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[16] | |||
| Compound Name |
10-[(3S)-1-Azabicyclo[2.2.2]octan-3-yl]-1,2,10-triazatricyclo[6.4.1.04,13]trideca-2,4(13),5,7-tetraen-9-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3261481; SCHEMBL6920090; BDBM50014550
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| Activity |
IC50 ~ 50000 nM
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[13] | |||
| Compound Name |
6-Methyl-2-(pyridin-2-ylmethylsulfanyl)-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
compound 30 [PMID: 22239545]; CHEMBL2019024; GTPL8749; ZINC6276192; BDBM50380515; AKOS001373830; MCULE-1344498176; ST51029294; 5-methyl-2-(2-pyridylmethylthio)benzimidazole; J3.516.543F; 2-(2-Pyridinylmethylthio)-6-methyl-1H-benzoimidazole; 5-methyl-2-(2-pyridylmethylsulfanyl)-1H-benzimidazole; Q27076550; 1H-Benzimidazole, 5-methyl-2-[(2-pyridinylmethyl)thio]-; 5-Methyl-2-((pyridin-2-ylmethyl)thio)-1H-benzo[d]imidazole
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| Activity |
IC50 = 50000 nM
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[14] | |||
| Compound Name |
10-[(3S)-1-Azabicyclo[2.2.2]octan-3-yl]-1,3,10-triazatricyclo[6.4.1.04,13]trideca-4,6,8(13)-triene-2,9-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3261486; SCHEMBL6919520; BDBM50014556
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| Activity |
IC50 ~ 50000 nM
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[13] | |||
| Compound Name |
2-(Cyclopropylmethylsulfanyl)-6-methoxy-1H-benzimidazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2018911; BDBM50380525
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| Activity |
IC50 = 50000 nM
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[14] | |||
| Compound Name |
10-[(3S)-1-Azabicyclo[2.2.2]octan-3-yl]-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4(13),5,7-tetraen-9-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3261479; SCHEMBL6919475; BDBM50014548
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| Activity |
IC50 ~ 50000 nM
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[13] | |||
| Compound Name |
10-[(3S)-1-Azabicyclo[2.2.2]octan-3-yl]-6-chloro-1,2,10-triazatricyclo[6.4.1.04,13]trideca-2,4(13),5,7-tetraen-9-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3261483; SCHEMBL6919297; BDBM50014552
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| Activity |
IC50 ~ 50000 nM
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[13] | |||
| Compound Name |
CID 57519510
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Investigative | Compound Info | ||
| Synonyms |
SR-3306; CHEMBL2144409; MLS006012045; SCHEMBL3750574; BDBM50059654; ZINC72317307; SB17012; NCGC00263146-01; HY-12829; SMR004703567
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| Activity |
IC50 ~ 50000 nM
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[17] | |||
| Compound Name |
3-(1H-Imidazol-4-yl)pyridine
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Investigative | Compound Info | ||
| Synonyms |
3-(1H-imidazol-5-yl)pyridine; 3-(5-Imidazolyl)pyridine; 4-(3-Pyridyl)imidazole; Pyridine, 3-(1H-imidazol-4-yl)-; CHEMBL178516; 3-(3H-imidazol-4-yl)-pyridine; 5(4)-3'-Pyridyl-glyoxaline; BRN 0003724; 4pyridin-3-yl-imidazole; 5-(3-pyridyl)imidazole; 3-(4-imidazolyl)pyridine; 4-pyridin-3-yl-imidazole; 5-[Pyridin-3-yl]imidazole; 4-26-00-00176 (Beilstein Handbook Reference); JMC514968 Compound 7; SCHEMBL464452; BDBM12357; CTK4J4760; CTK5J6616; KS-00000JFZ; DTXSID20199682; 3-(1H-Imidazol-4-yl)-pyridine; BCP09804; Pyridine,3-(1H-imidazol-5-yl)-; ANW-74866; BBL102223; MFCD10565593; Pyridine, 3-(1H-imidazol-5-yl)-; SBB086411; STL556022; ZINC13607121; AKOS006237191; AKOS015962782; nicotine 3-heteroaromatic analogue 10; CS-W021752; VP11174; AC-17591; AK-35428; MS-20400; SC-12023; 2-(TRIPHENYLPHOSPHONIO)ETHYLCHLORO-; AM20061273; FT-0670298; US8609708,14; US8609708, 14; 746I851; A828746; J-513404
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| Activity |
Ki = 51500 nM
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[10] | |||
| Compound Name |
N-(1-((5-Cyanopyridin-2-yl)methyl)-1H-pyrazol-3-yl)-2-(4-(1-(trifluoromethyl)cyclopropyl)-phenyl)acetamide
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Investigative | Compound Info | ||
| Synonyms |
ACT-709478; UNII-3Z7U1U8Z9E; 3Z7U1U8Z9E; CHEMBL4217292; SCHEMBL17316866; BCP30302; EX-A3130; BDBM50452245; ACT 709478; BS-16157; HY-112723; CS-0062884; ACT709478; ACT 709478
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| Activity |
IC50 = 52000 nM
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[18] | |||
| Compound Name |
(5-Pyrid-3-ylthien-2-YL)methylamine
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Investigative | Compound Info | ||
| Synonyms |
(5-pyridin-3-ylthiophen-2-yl)methanamine; [5-(3-pyridyl)-2-thienyl]methanamine; compound 38a [PMID: 15634016]; CHEMBL359657; [5-(pyridin-3-yl)thiophen-2-yl]methanamine; (5-(pyridin-3-yl)thiophen-2-yl)methanamine; GTPL8755; SCHEMBL3610698; BDBM12341; CTK5F1053; DTXSID90458692; MFCD09879956; SBB070321; ZINC12370797; nicotine 3-heteroaromatic analogue 1a; AKOS006282357; (5-(3-pyridyl)-2-thienyl)methylamine; 2-Thiophenemethanamine,5-(3-pyridinyl)-; SC-51874; 2-Thiophenemethanamine, 5-(3-pyridinyl)-; DB-075967; FT-0695394; US8609708, 1; US8609708, 31; Q27076597
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| Activity |
IC50 = 52200 nM
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[19] | |||
| Compound Name |
(6-Hydroxy-1,3-benzothiazol-2-yl)-(3-hydroxy-4-methylphenyl)methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2170754; SCHEMBL29654; BDBM50396080
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| Activity |
IC50 = 54000 nM
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[20] | |||
| Compound Name |
(4-Fluoro-3-hydroxyphenyl)-(6-hydroxy-1,3-benzothiazol-2-yl)methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2170750; SCHEMBL29673; BDBM50396084
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| Activity |
IC50 = 54000 nM
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[20] | |||
| Compound Name |
2,6-Difluoro-3-hydroxy-N-(6-hydroxy-1,3-benzothiazol-2-yl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2170747; SCHEMBL29964; BDBM50396087
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| Activity |
IC50 = 54000 nM
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[20] | |||
| Compound Name |
3-(3-Thienyl)pyridine
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Investigative | Compound Info | ||
| Synonyms |
3-(thiophen-3-yl)pyridine; 3-thiophen-3-ylpyridine; 3-(thiophene-3-yl)pyridine; Pyridine, 3-(3-thienyl)-; CHEMBL361153; 3-(3-thienyl)-pyridine; 3-(Thien-3-yl)pyridine; SCHEMBL2777912; BDBM12355; CTK0J7722; DTXSID20344236; MFCD06802559; nicotine 3-heteroaromatic analogue 8; ZINC13607083; AKOS004118749; DB-066480; FT-0738684; US8609708,11; Z2618249113
Click to Show/Hide
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||||
| Activity |
IC50 = 59100 nM
|
[21] | |||
| Compound Name |
N-Methyl-3-(3-pyridinyl)-2-propyne-1-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL149808; SCHEMBL3613286; BDBM12349; nicotine 3-heteroaromatic analogue 3b; AKOS006353806; N-methyl-3-pyridin-3-ylprop-2-yn-1-amine; methyl[3-(pyridin-3-yl)prop-2-yn-1-yl]amine; N-methyl-3-(pyridin-3-yl)prop-2-yn-1-amine; US8609708, 26
Click to Show/Hide
|
||||
| Activity |
Ki = 60000 nM
|
[10] | |||
| Compound Name |
CID 16041411
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2434978; SCHEMBL5575492; BDBM50441716
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[22] | |||
| Compound Name |
(3-(Pyridin-3-yl)-1H-pyrazol-5-yl)methanamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
[3-(pyridin-3-yl)-1H-pyrazol-5-yl]methanamine; CHEMBL385008; SCHEMBL3608558; BDBM12370; ZINC14949866; AKOS011391775; nicotine 3-heteroaromatic analogue 32; (3-pyridin-3-yl-1H-pyrazol-5-yl)methanamine; 1H-Pyrazole-5-methanamine, 3-(3-pyridinyl)-; F2198-0506; [3-(3-pyridyl)-1H-pyrazol-5-yl]methylamine;hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 = 66400 nM
|
[19] | |||
| Compound Name |
1-(3-Pyridin-3-ylisoxazol-5-YL)methanamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBRDG-BB 4010763; (3-pyridin-3-yl-1,2-oxazol-5-yl)methanamine; (3-(Pyridin-3-yl)isoxazol-5-yl)methanamine dihydrochloride; CHEMBL217125; SCHEMBL2121672; BDBM12371; CTK5A0710; DTXSID70475408; HMS3741G15; ZINC14949869; AKOS013154320; nicotine 3-heteroaromatic analogue 35; [3-(3-pyridyl)isoxazol-5-yl]methylamine; MLS-0091929.0001; Y-3396; 1-[3-(Pyridin-3-yl)-1,2-oxazol-5-yl]methanamine; [3-(pyridin-3-yl)-1,2-oxazol-5-yl]methanamine dihydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 = 67400 nM
|
[19] | |||
| Compound Name |
(2E,5E)-2,5-Bis[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]cyclopentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000374615; CHEMBL498373; SMR000244230; NSC705591; BDBM32312; cid_2407524; HMS2553D13; NSC-705591; 2,5-Bis(3,5-dimethoxy-4-hydroxybenzylidene)cyclopentanone; (2E,5E)-2,5-bis(4-hydroxy-3,5-dimethoxy-benzylidene)cyclopentanone; (2E,5E)-2,5-bis[(3,5-dimethoxy-4-oxidanyl-phenyl)methylidene]cyclopentan-1-one; (2E,5E)-2,5-bis[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-1-cyclopentanone
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[23] | |||
| Compound Name |
3-(2-Thienyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-(THIOPHEN-2-YL)PYRIDINE; 3-thiophen-2-ylpyridine; 2-(3-pyridyl)thiophene; 3-(2-thienyl)-pyridine; 3-thiophen-2-yl-pyridine; Pyridine,3-(2-thienyl)-; CHEMBL179618; MFCD01860052; 3-thien-2-ylpyridine; ACMC-1CLKC; 7-Fluoro-6-methylisatin; 3-Thiophene-2-yl-pyridine; Pyridine, 3-(2-thienyl)-; SCHEMBL158705; CTK4E6374; DTXSID20344216; ZINC334312; BDBM50158919; SBB087543; AKOS004118920; MCULE-2037557762; VP14424; AC-29170; AS-58501; ST095204; DB-045533; FT-0613597; US8609708, 33; A815253; AI-942/25034651
Click to Show/Hide
|
||||
| Activity |
IC50 = 70800 nM
|
[21] | |||
| Compound Name |
3-(1H-Pyrazol-3-yl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-(1H-pyrazol-5-yl)pyridine; MFCD03407951; 3pypz; 3-(3-pyridyl)pyrazole; 3-(pyridin-3-yl)pyrazole; SCHEMBL446537; 3-(3-Pyridyl)-1H-pyrazole; CHEMBL218397; 5-(3-Pyridinyl)-1H-pyrazole; SCHEMBL13425468; 3-(1h pyrazol-3-yl)-pyridine; 3-(1H-pyrazol-3-yl)-pyridine; BDBM12368; CTK4I8991; DTXSID80427736; Pyridine,3-(1H-pyrazol-3-yl)-; ALBB-013294; KS-00001X6F; ZINC9238272; 6312AB; ANW-44766; BBL029970; SBB086413; STL303694; AKOS000345412; AKOS005174219; nicotine 3-heteroaromatic analogue 27; AB14049; AC-5755; ACN-000481; MCULE-8439479564; VP12631; 3-(1H-Pyrazol-3-yl)pyridine, AldrichCPR; AB0157775; DB-011092; PYRIDINE, 3-(1H-PYRAZOL-3-YL)-; CS-0110791; FT-0683682; EN300-36077; A12267; MLS-0091915.0001; Y-5619; 4Y-0803; 887P089
Click to Show/Hide
|
||||
| Activity |
Ki = 71500 nM
|
[10] | |||
| Compound Name |
Pyridine, 2-fluoro-5-(3-thienyl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL179005; 2-fluoro-5-thiophen-3-yl-pyridine; SCHEMBL3601434; 2-Fluoro-5-(3-thienyl)pyridine; 2-fluoro-5-thiophen-3-ylpyridine; BDBM50158913; 2-fluoro-5-(thiophen-3-yl)pyridine; US8609708, 28
Click to Show/Hide
|
||||
| Activity |
IC50 = 72100 nM
|
[21] | |||
| Compound Name |
4-[[6-Ethyl-5-[[4-[(5R)-2-oxo-5-phenyl-3-(tetrahydro-2H-pyran-4-yl)imidazolidine-1-yl]piperidino]methyl]pyridine-2-yl]oxy]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2435856; SCHEMBL5576709; BDBM50441713
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 73000 nM
|
[22] | |||
| Compound Name |
Pyridine, 3-(1-methyl-1H-imidazol-4-yl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL360999; 3-(1-methylimidazol-4-yl)pyridine; 3-(1-methyl-1H-imidazol-4-yl)pyridine; SCHEMBL3644924; BDBM12352; CTK2I3860; DTXSID90462916; cid_11344157; nicotine 3-heteroaromatic analogue 5; MLS-0091928.0001; US8609708, 5
Click to Show/Hide
|
||||
| Activity |
Ki = 73000 nM
|
[10] | |||
| Compound Name |
2,5-Bis(3,5-diisopropyl-4-hydroxybenzylidene)cyclopentanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL498371; BDBM50265001; 2,5-bis(4-hydroxy-3,5-diisopropylbenzylidene)cyclopentanone
Click to Show/Hide
|
||||
| Activity |
IC50 = 74300 nM
|
[23] | |||
| Compound Name |
3-(1-Ethyl-1H-imidazol-4-yl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL361364; Pyridine, 3-(1-ethyl-1H-imidazol-4-yl)-; 3-(1-ethylimidazol-4-yl)pyridine; SCHEMBL3604362; CTK3D1371; DTXSID80467192; cid_11480732; BDBM50158928; 3-(1-Ethyl-1H-imidazol-4-yl)-pyridine; MLS-0091930.0001; US8609708, 20
Click to Show/Hide
|
||||
| Activity |
IC50 = 83100 nM
|
[21] | |||
| Compound Name |
Chembl4288001
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50466485
Click to Show/Hide
|
||||
| Activity |
IC50 = 84700 nM
|
[24] | |||
| Compound Name |
CYP3cide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
PF-4981517; PF-04981517; UNII-ZRD2TT3Y1T; ZRD2TT3Y1T; CHEMBL3527048; PF 4981517; C26H32N8; SCHEMBL15522135; DTXSID60747404; SYN3007; CYP3cide;PF-04981517; CYP3cide, >=98% (HPLC); 2645AH; BDBM50088503; MFCD22417344; s2921; ZINC77286311; AKOS024458057; CCG-269301; SB16511; NCGC00379101-02; AS-16353; HY-18642; CS-0011640; SW219546-1; PF 04981517
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[25] | |||
| Compound Name |
N-(2-(4-(4-(3,4-Dimethoxybenzyl)piperazin-1-yl)phenylcarbamoyl)phenyl)quinoline-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL266212; BDBM50209506
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
2-[[4-[[6-Amino-2-(2-methoxyethoxy)-8-oxo-7H-purin-9-yl]methyl]benzoyl]amino]ethoxy-[3,4-di(dodecanoyloxy)butyl]phosphinic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4107005; BDBM189322; US9173935, SC12
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
[3-[2-[[4-[[6-Amino-2-(2-methoxyethoxy)-8-oxo-7H-purin-9-yl]methyl]benzoyl]amino]ethoxy-hydroxyphosphoryl]oxy-2-dodecanoyloxypropyl] dodecanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4106421; BDBM190404; US9180183, SC12
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
4-[[6-Methyl-5-[[4-[(5R)-2-oxo-5-(3-chlorophenyl)-3-(tetrahydro-2H-pyran-4-yl)imidazolidine-1-yl]piperidino]methyl]pyridine-2-yl]oxy]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2435853; SCHEMBL5575383; BDBM50441719
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
2-[4-[4-[6-[[2-Phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carbonyl]amino]-1H-benzimidazol-2-yl]phenyl]cyclohexyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2409564; BDBM50437753; KR-69232
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[28] | |||
| Compound Name |
Chembl4177457
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL15416328; BDBM50276954; 1-[[5-chloro-1-(oxetan-3-ylmethyl)benzimidazol-2-yl]methyl]-3-methylsulfonylpyrazolo[3,4-c]pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
JTZ-951 HCl
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4166742; 1262131-60-1 (HCl); (7-Hydroxy-5-phenethyl-[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl)glycine hydrochloride; JTZ-951 hydrochloride; SCHEMBL1481939; BDBM50286071
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
2-[5-Fluoro-2-methyl-3-(1-oxo-2-propan-2-ylisoquinolin-4-yl)indol-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3236948; SCHEMBL1757378; CRA-680; BDBM50006830; 2-(5-fluoro-3-(2-isopropyl-1-oxo-1,2-dihydroisoquinolin-4-yl)-2-methyl-1H-indol-1-yl)acetic acid
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[31] | |||
| Compound Name |
Vibegron
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
KRP-114V; UNII-M5TSE03W5U; MK-4618; M5TSE03W5U; MK4618; C26H28N4O3; Vibegron [USAN:INN]; vibegronum; Beova; Beova (TN); MK 4618; Vibegron (JAN/USAN); CHEMBL2107826; SCHEMBL11985457; GTPL10100; DTXSID40152299; EX-A3390; BDBM50146154; MFCD28502057; compound 7 [PMID: 26709102]; DB14895; SB16922; D10433; Q27283524
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[32] | |||
| Compound Name |
N-(2-((2-((3,4-Dimethoxyphenethyl)(methyl)amino)ethyl)carbamoyl)phenyl)quinoline-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL244239; BDBM50209505
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
N-(2-(4-(4-(3,4-Dimethoxybenzyl)piperazin-1-yl)phenylcarbamoyl)-4,5-dimethoxyphenyl)quinoline-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL242983; BDBM50209508
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[8] | |||
| Compound Name |
2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
PF-06282999; UNII-YO3O4Q2NC8; YO3O4Q2NC8; CHEMBL3633460; PF06282999; 2-[6-(5-chloro-2-methoxyphenyl)-4-oxo-2-sulfanylidenepyrimidin-1-yl]acetamide; SCHEMBL14936135; GTPL10053; BCP20203; EX-A2535; BDBM50133595; s6648; ZINC205775084; compound 8 [PMID: 26509551]; CS-6095; DB11683; BS-15745; HY-19321; J3.552.697H; Q27294622
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[33] | |||
| Compound Name |
(1S,4S,5R,8S,9R,10S,12R,13R)-1,5,9-Trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecan-10-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Artenimol; Dihydroartemisinin; GNF-PF-5634; Artemether related compound a; CHEMBL252518; SCHEMBL19937859; ZINC100036938; Z2471178870
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 125000 nM
|
[34] | |||
| Compound Name |
(NZ)-N-[(5-pyridin-3-ylfuran-2-yl)methylidene]hydroxylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL178330; SCHEMBL13035362
Click to Show/Hide
|
||||
| Activity |
IC50 = 128000 nM
|
[21] | |||
| Compound Name |
3,3'-Bipyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3,3'-Bipyridyl; 3,3'-Dipyridyl; [3,3']Bipyridinyl; 3-pyridin-3-ylpyridine; UNII-7B4E4PPN49; 7B4E4PPN49; CHEMBL179763; 3,3'-Dipyridine; CCRIS 3427; EINECS 209-466-1; 3,3'-Diphridyl; 3-(3-pyridyl)pyridine; ChemDiv3_000071; 3-(pyridin-3-yl)pyridine; [3,3'''']Bipyridinyl; MLS000084686; SCHEMBL120088; CTK1H3030; DTXSID80206821; HMS1473D05; HMS2388I13; ZINC262514; BDBM50158918; MFCD00006371; AKOS006282824; MCULE-2048309802; IDI1_019389; KS-000012B8; NCGC00043241-02; AC-20964; AS-56903; SMR000019033; 3,3 inverted exclamation mark(R)-bipyridine; B3984; EU-0066981; US8609708, 30; Q222984; SR-01000390733; J-511054; SR-01000390733-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 145000 nM
|
[21] | |||
| Compound Name |
3-(3-Methyl-1H-imidazol-4-yl)-pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL179399; BDBM50158920
Click to Show/Hide
|
||||
| Activity |
IC50 = 146000 nM
|
[21] | |||
| Compound Name |
N-Methyl(5-(pyridin-3-yl)furan-2-yl)methanamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL178938; 2-Furanmethanamine, N-methyl-5-(3-pyridinyl)-; methyl({[5-(pyridin-3-yl)furan-2-yl]methyl})amine; SCHEMBL3608219; BDBM12346; nicotine 3-heteroaromatic analogue 2b; DB07617; US8609708,16; N-methyl-1-(5-pyridin-3-ylfuran-2-yl)methanamine; Q27096837
Click to Show/Hide
|
||||
| Activity |
Ki = 179000 nM
|
[10] | |||
| Compound Name |
Dimethyl[3-(pyridin-3-yl)prop-2-yn-1-yl]amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL180270; 2-Propyn-1-amine, N,N-dimethyl-3-(3-pyridinyl)-; SCHEMBL3619456; BDBM12350; nicotine 3-heteroaromatic analogue 3c; N,N-dimethyl-3-pyridin-3-ylprop-2-yn-1-amine; US8609708, 76; N,N-Dimethyl-3-(3-pyridinyl)-2-propyne-1-amine; N,N-dimethyl-3-(pyridin-3-yl)prop-2-yn-1-amine
Click to Show/Hide
|
||||
| Activity |
Ki = 192000 nM
|
[10] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 16 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
GW803430
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6-(4-Chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)thieno[3,2-d]pyrimidin-4(3H)-one; 515141-51-2; GW 803430; GW-3430; UNII-4R0136W1PR; GW-803430; Thieno[3,2-d]pyrimidin-4(3H)-one, 6-(4-chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-; CHEMBL214957; GW-803,430; 4R0136W1PR; GW3430; 6-(4-Chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)thieno(3,2-d)pyrimidin-4(3H)-one; 6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)thieno[3,2-d]pyrimidin-4(3H)-one; Thieno(3,2-d)pyrimidin-4(3H)-one,; GW-803,430
Click to Show/Hide
|
||||
| Activity |
IC50 > 10000000 nM
|
[35] | |||
| Compound Name |
Auglurant
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
VU0424238; N-(5-fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide; CHEMBL2386850; UNII-GRN8X62ZW2; GRN8X62ZW2; SCHEMBL12499337; VU238; EX-A2936; BDBM50257064; MFCD28386341; VU 238; 2-PyridinecarboxaMide, N-(5-fluoro-2-pyridinyl)-6-Methyl-4-(5-pyriMidinyloxy)-; HY-16617; CS-0009173; VU 0424238; YU-0424238; J3.655.475D; 2-PyridinecarboxaMide,N-(5-fluoro-2-pyridinyl)-6-Methyl-4-(5-pyriMidinyloxy)-; N-(5-Fluoro-2-pyridinyl)-6-methyl-4-(5-pyrimidinyloxy)-2-pyridinecarboxamide; N-(5-fluoropyridin-2-yl)-6-methyl-4-pyrimidin-5-yloxypyridine-2-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[36] | |||
| Compound Name |
5-Hydroxy saxagliptin
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|
Investigative | Compound Info | ||
| Synonyms |
UNII-PB91NV4HAN; PB91NV4HAN; Saxagliptin analogue 28; Saxagliptin metabolite M2; CHEMBL3350936; SCHEMBL13096265; BDBM11543; M2 saxagliptin hydroxylated metabolite; BMS 510849; (S)-3,5-Dihydroxyadamantylglycine-L-cis-4,5-methanoprolinenitrile TFA salt
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[3] | |||
| Compound Name |
(NE)-N-[(5-pyridin-3-ylfuran-2-yl)methylidene]hydroxylamine;(NZ)-N-[(5-pyridin-3-ylfuran-2-yl)methylidene]hydroxylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1795039
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|
||||
| Activity |
IC50 = 206000 nM
|
[21] | |||
| Compound Name |
1-(5-(Pyridin-3-yl)thiophen-2-yl)ethan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL362702; SCHEMBL3649364; BDBM50158912; ZINC13607079; AKOS026718588; 1-(5-pyridin-3-ylthiophen-2-yl)ethanone; 1-(5-Pyridin-3-yl-thiophen-2-yl)-ethanone; Ethanone, 1-[5-(3-pyridinyl)-2-thienyl]-; US8609708, 36; F2167-0965
Click to Show/Hide
|
||||
| Activity |
IC50 = 217000 nM
|
[21] | |||
| Compound Name |
(5-Pyridin-3-ylthiophen-2-yl)methanamine;(5-pyridin-3-ylthiophen-2-yl)methanimine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL178681
Click to Show/Hide
|
||||
| Activity |
IC50 = 256000 nM
|
[21] | |||
| Compound Name |
Pyridine, 3-(4-methyl-1H-imidazol-1-yl)-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL178781; SCHEMBL3617491; 3-(4-methylimidazol-1-yl)pyridine; BDBM50158922; 3-(4-Methyl-imidazol-1-yl)-pyridine
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| Activity |
IC50 > 300000 nM
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[21] | |||
| Compound Name |
3-(2-Methyl-1H-imidazol-1-yl)pyridine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL368883; Pyridine, 3-(2-methyl-1H-imidazol-1-yl)-; 3-(2-methylimidazol-1-yl)pyridine; SCHEMBL3609259; BDBM12356; CTK3D1370; DTXSID90586500; cid_16654686; nicotine 3-heteroaromatic analogue 9; ZINC13607175; AKOS033848776; MLS-0091920.0001; US8609708,13; Z2284398422
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| Activity |
Ki > 300000 nM
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[10] | |||
| Compound Name |
Chembl4170930
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Investigative | Compound Info | ||
| Synonyms |
BDBM50366397
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| Activity |
IC50 = 364000 nM
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[37] | |||
| Compound Name |
N,N-Dimethyl(5-(pyridin-3-yl)furan-2-yl)methanamine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL360998; 2-Furanmethanamine, N,N-dimethyl-5-(3-pyridinyl)-; dimethyl({[5-(pyridin-3-yl)furan-2-yl]methyl})amine; SCHEMBL3604825; BDBM12347; nicotine 3-heteroaromatic analogue 2c; DB07609; US8609708, 56; Q27096829; N,N-dimethyl-1-(5-pyridin-3-ylfuran-2-yl)methanamine
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| Activity |
Ki > 400000 nM
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[10] | |||
| Compound Name |
Dimethyl({[5-(pyridin-3-yl)thiophen-2-yl]methyl})amine
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL361969; SCHEMBL3618712; 2-Thiophenemethanamine, N,N-dimethyl-5-(3-pyridinyl)-; BDBM12344; N,N-dimethyl-1-(5-pyridin-3-ylthiophen-2-yl)methanamine; nicotine 3-heteroaromatic analogue 1c; US8609708, 75; N,N-dimethyl(5-(pyridin-3-yl)thiophen-2-yl)methanamine
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| Activity |
Ki > 400000 nM
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[10] | |||
| Compound Name |
3-(Pyridin-3-yl)propan-1-amine
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Investigative | Compound Info | ||
| Synonyms |
3-(3-PYRIDYL)PROPYLAMINE; 3-PYRIDINEPROPANAMINE; 3-PYRIDIN-3-YLPROPAN-1-AMINE; 3-PYRIDIN-3-YL-PROPYLAMINE; MFCD09886637; 3-(3-PYRIDINYL)-1-PROPANAMINE; 3-pyridylpropylamine; 3-pyridine propanamine; 3-Pyridine-1-propanamine; 3-(3-pyridinyl)propanamine; CHEMBL385023; SCHEMBL1188053; BDBM12369; KS-00000DVE; DTXSID50543790; 3-(pyridine-3-yl)propan-1-amine; (3-PYRIDIN-3-YLPROPYL)AMINE; ZINC11570838; AKOS005216860; nicotine 3-heteroaromatic analogue 30; AB54556; MCULE-1632771311; (3-pyridin-3-ylpropyl)amine AldrichCPR; (3-pyridin-3-ylpropyl)amine, AldrichCPR; AK105794; AS-32159; SC-49861; SY022422; X2118; Y-5938
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| Activity |
Ki > 400000 nM
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[10] | |||
| Compound Name |
N-Methyl-(5-pyrid-3-ylthien-2-yl)methylamine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL369285; N-methyl-1-(5-pyridin-3-ylthiophen-2-yl)methanamine; 2-[(Methylamino)methyl]-5-pyridin-3-ylthiophene; SCHEMBL3607664; methyl({[5-(pyridin-3-yl)thiophen-2-yl]methyl})amine; BDBM12343; CTK5F1054; DTXSID50462275; MFCD11109328; SBB093353; ZINC13607141; nicotine 3-heteroaromatic analogue 1b; DB-075968; FT-0763000; US8609708, 9; methyl[(5-(3-pyridyl)(2-thienyl))methyl]amine; 2-Thiophenemethanamine,N-methyl-5-(3-pyridinyl)-; 2-Thiophenemethanamine, N-methyl-5-(3-pyridinyl)-; N-methyl(5-(pyridin-3-yl)thiophen-2-yl)methanamine; N-Methyl-1-[5-(pyridin-3-yl)thiophen-2-yl]methanamine
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| Activity |
Ki > 400000 nM
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[10] | |||
| Compound Name |
1-(1-(2-(Pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)-4-(4-(trifluoromethyl)phenyl)pyridin-2(1H)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1290041; SCHEMBL10144508; BDBM50331168
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| Activity |
IC50 > 10000000 nM
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[35] | |||
| Compound Name |
1-[1-(4-Cyanophenyl)-4-bicyclo[3.1.0]hexanyl]-3-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[3-(4-methylpiperazin-1-yl)propyl]urea
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL136046; CHEMBL1289614
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| Activity |
IC50 > 10000000 nM
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[35] | |||
| Compound Name |
4-(2,4-Dichlorophenyl)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1290150; SCHEMBL10144391; BDBM50331170
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| Activity |
IC50 > 10000000 nM
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[35] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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